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ARFGAP2 Knockout Cell Lines

Gene: ARFGAP2

Official Full Name: ARF GTPase activating protein 2provided by HGNC

Gene Summary: Predicted to enable GTPase activator activity. Predicted to be involved in COPI coating of Golgi vesicle. Located in Golgi apparatus; cytosol; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24896 ARFGAP2 Knockout cell line (HeLa) Human ARFGAP2 1:3~1:6 Negative Online Inquiry
KO24897 ARFGAP2 Knockout cell line (HCT 116) Human ARFGAP2 1:2~1:4 Negative Online Inquiry
KO24898 ARFGAP2 Knockout cell line (HEK293) Human ARFGAP2 1:3~1:6 Negative Online Inquiry
KO24899 ARFGAP2 Knockout cell line (A549) Human ARFGAP2 1:3~1:4 Negative Online Inquiry

Background

ARFGAP2 Gene Knockout Cell Lines are genetically modified cell lines designed specifically to provide researchers with powerful tools for investigating the biological functions of the ARFGAP2 gene and its role in cellular processes. Through the precise editing of the genome using CRISPR-Cas9 technology, these cell lines have the ARFGAP2 gene entirely removed, facilitating comprehensive studies on the gene's contributions to vesicle trafficking, cellular signaling, and metabolism.

The primary function of ARFGAP2 involves the regulation of the ARF (ADP-ribosylation factor) protein family, which plays a crucial role in membrane traffic and cytoskeletal organization. By utilizing ARFGAP2 knockout cells, researchers can explore the upstream and downstream effects of this gene's absence, enabling insights into complex cellular mechanisms involved in various physiological and pathological conditions, including cancer progression and neurodegenerative diseases.

The scientific importance of ARFGAP2 Gene Knockout Cell Lines extends to their applicability in both basic and translational research. They serve as a platform for drug screening, target validation, and the development of gene therapies. Moreover, these cell lines allow for the assessment of compensatory pathways activated in the absence of ARFGAP2, thereby unveiling potential therapeutic targets for intervention.

One of the significant advantages of our ARFGAP2 Gene Knockout Cell Lines is their high fidelity and specificity, ensuring that researchers can trust their results. Unlike alternative silencing approaches, such as RNA interference, which may lead to off-target effects, our knockout model provides a clean and definitive assessment of gene function. Additionally, our cell lines are rigorously validated, ensuring reproducibility and consistency across experiments.

For researchers and clinicians seeking a reliable model for studying ARFGAP2-related cellular processes, these knockout cell lines are invaluable. They present a unique opportunity to deepen our understanding of ARFGAP2’s intricate roles in health and disease, ultimately paving the way for novel therapeutic strategies.

At [Your Company Name], we are dedicated to providing high-quality genetic tools that empower scientific discovery. With years of expertise in genetic engineering and a commitment to advancing biomedical research, our ARFGAP2 Gene Knockout Cell Lines exemplify our mission to support groundbreaking research with precision and reliability.

Please note that all services are for research use only. Not intended for any clinical use.

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