Gene: APOO
Official Full Name: apolipoprotein Oprovided by HGNC
Gene Summary: This gene is a member of the apolipoprotein family. Members of this protein family are involved in the transport and metabolism of lipids. The encoded protein associates with HDL, LDL and VLDL lipoproteins and is characterized by chondroitin-sulfate glycosylation. This protein may be involved in preventing lipid accumulation in the myocardium in obese and diabetic patients. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 3, 4, 5, 12 and 16.[provided by RefSeq, Sep 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO19758 | APOO Knockout cell line (HeLa) | Human | APOO | 1:3~1:6 | Negative | Online Inquiry |
KO19759 | APOO Knockout cell line (HCT 116) | Human | APOO | 1:2~1:4 | Negative | Online Inquiry |
KO19760 | APOO Knockout cell line (HEK293) | Human | APOO | 1:3~1:6 | Negative | Online Inquiry |
KO19761 | APOO Knockout cell line (A549) | Human | APOO | 1:3~1:4 | Negative | Online Inquiry |
APOO Gene Knockout Cell Lines represent a pioneering and essential tool in the field of molecular biology, designed for researchers aiming to elucidate the functional roles of the APOO gene. These cell lines are engineered to exhibit a complete knockout of the APOO gene, utilizing advanced CRISPR-Cas9 technology to achieve precise gene editing. By knocking out the APOO gene, researchers can study the gene's involvement in various biological processes, including lipid metabolism, immune response, and cell signaling pathways.
The key mechanism underlying the functionality of these knockout cell lines hinges on the targeted disruption of the APOO gene, which allows for the analysis of phenotypic changes and the assessment of gene function in various cellular contexts. This approach enables scientists to investigate the profound effects of the absence of APOO, facilitating insights into disease mechanisms and potential therapeutic targets.
The scientific importance of APOO Gene Knockout Cell Lines is multifaceted. In research settings, these cell lines are invaluable for studying diseases associated with APOO dysfunction, including metabolic disorders and cardiovascular diseases. In clinical applications, findings from these studies can pave the way for innovations in gene therapy and personalized medicine, as understanding gene roles in disease can lead to targeted treatment strategies.
Compared to alternative models, such as traditional knockout mice or transient gene silencing techniques, our APOO Gene Knockout Cell Lines offer several key advantages. They provide faster results with lower costs, enable high-throughput screening, and allow for a more straightforward manipulation of cellular conditions. This product's accessibility and reproducibility further enhance its appeal, making it a prime choice for both academic and pharmaceutical research environments.
For researchers and clinicians, the value of APOO Gene Knockout Cell Lines lies in their ability to provide clarity in gene function analysis, thereby accelerating the pace of discovery in the realms of genetics and therapeutics. With a commitment to scientific excellence, our company brings a wealth of experience in developing high-quality biological products, ensuring that researchers have the tools they need to drive impactful discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
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