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APOL2 Knockout Cell Lines

Gene: APOL2

Official Full Name: apolipoprotein L2provided by HGNC

Gene Summary: This gene is a member of the apolipoprotein L gene family. The encoded protein is found in the cytoplasm, where it may affect the movement of lipids or allow the binding of lipids to organelles. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO04347 APOL2 Knockout cell line (HeLa) Human APOL2 1:3~1:6 Negative Online Inquiry
KO04348 APOL2 Knockout cell line (HCT 116) Human APOL2 1:2~1:4 Negative Online Inquiry
KO04349 APOL2 Knockout cell line (HEK293) Human APOL2 1:3~1:6 Negative Online Inquiry
KO04350 APOL2 Knockout cell line (A549) Human APOL2 1:3~1:4 Negative Online Inquiry

Background

APOL2 Gene Knockout Cell Lines are meticulously engineered cellular models designed to facilitate the study of the apolipoprotein L2 (APOL2) gene's function and its implications in various biological processes. APOL2 plays a crucial role in lipid metabolism and has been implicated in several pathophysiological conditions, including metabolic disorders and neurological diseases. These knockout cell lines are created through precise genome editing techniques, effectively disrupting the APOL2 gene to unravel its specific contributions and interactions within cellular pathways.

The primary function of the APOL2 Gene Knockout Cell Lines is to provide researchers with a robust tool for investigating the cellular mechanisms modulated by the APOL2 gene. By removing the gene's expression, scientists can scrutinize alterations in cellular behavior, lipid processing, and response to stressors, thereby gaining insights into its biological significance. This model enables in-depth analysis of phenotypic consequences and functional assays, allowing for a comprehensive understanding of APOL2-related signaling pathways.

The scientific importance of these knockout cell lines is underscored by their widespread applications in both basic and applied research settings. They serve as valuable resources for studying the molecular underpinnings of diseases linked to lipid dysregulation and facilitate the development of targeted therapeutic interventions. Researchers can leverage these model systems to investigate potential drug targets or the efficacy of pharmaceutical compounds aimed at mitigating the effects of APOL2 dysfunction.

What distinguishes the APOL2 Gene Knockout Cell Lines from alternative models is the precision and specificity of the knockout process, which enhances the reliability of experimental outcomes. Additionally, their versatility makes them suitable for a variety of assays, such as gene expression analysis, metabolic profiling, and cell viability studies, providing comprehensive data that can lead to significant breakthroughs in understanding APOL2's role in health and disease.

For researchers and clinicians focused on lipid-related diseases, the utility of APOL2 Gene Knockout Cell Lines cannot be overstated. They offer an unparalleled opportunity to advance scientific knowledge while potentially influencing therapeutic strategies in clinical settings. Our company brings years of expertise in developing cutting-edge biological products, ensuring that each product not only meets the rigorous standards of scientific research but also equips users with essential tools for their innovative investigations.

Please note that all services are for research use only. Not intended for any clinical use.

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