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ANP32A Knockout Cell Lines

Gene: ANP32A

Official Full Name: acidic nuclear phosphoprotein 32 family member Bprovided by HGNC

Gene Summary: Enables RNA polymerase binding activity and histone binding activity. Involved in several processes, including nucleosome assembly; positive regulation of cysteine-type endopeptidase activity; and positive regulation of protein export from nucleus. Located in cytoplasm; nucleolus; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00008 ANP32A Knockout cell line (293T) Human ANP32A 1:3~1:6 Negative Online Inquiry
KO00988 ANP32A Knockout cell line (A549) Human ANP32A 1:3~1:4 Negative Online Inquiry
KO01310 ANP32A Knockout cell line(MDCK) Dog ANP32A 1:3~1:4 Negative Online Inquiry
KO34309 ANP32A Knockout cell line (HeLa) Human ANP32A 1:3~1:6 Negative Online Inquiry
KO34310 ANP32A Knockout cell line (HCT 116) Human ANP32A 1:2~1:4 Negative Online Inquiry
KO34311 ANP32A Knockout cell line (HEK293) Human ANP32A 1:3~1:6 Negative Online Inquiry

Background

ANP32A Gene Knockout Cell Lines are genetically modified cell models in which the ANP32A gene, a crucial component involved in various cellular processes, including RNA metabolism and regulation, has been inactivated. This innovative product provides scientists with a powerful tool to study the specific roles of ANP32A in cellular pathways and its implications in various biological contexts, such as viral infections, cancer development, and neurological disorders.

The mechanism underlying the function of ANP32A involves its interaction with various cellular molecules, influencing transcriptional and post-transcriptional regulatory mechanisms. By creating knockout models, researchers can dissect the resultant phenotypic changes, thereby elucidating the gene's function and its contribution to cellular homeostasis. The ANP32A gene knockout cell lines are instrumental in facilitating high-throughput screening and drug discovery, enabling researchers to identify potential therapeutic targets and evaluate the efficacy of experimental compounds.

The scientific importance of these cell lines is underscored by their broad applicability in research settings, particularly in studies related to cancer biology and viral pathogenesis, where ANP32A plays a pivotal role. In clinical settings, understanding the function of this gene could pave the way for novel therapeutic strategies for diseases linked to its dysfunction.

Compared to alternative approaches, such as the use of broad-spectrum inhibitors or wild-type cell lines, the ANP32A Gene Knockout Cell Lines provide precise, targeted insights into gene function without the ambiguity associated with off-target effects. This specificity enhances the reliability of experimental outcomes, making these cell lines an invaluable resource for both fundamental and applied biological research.

Ultimately, ANP32A Gene Knockout Cell Lines are a testament to our commitment to advancing scientific research through high-quality, reliable products. Our expertise in genetic modification and commitment to providing advanced biotechnological solutions positions us as a leading provider of biological products, empowering researchers and clinicians to push the boundaries of discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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