Gene: ANKRD34A
Official Full Name: ankyrin repeat domain 34Aprovided by HGNC
Gene Summary: Predicted to be active in pi-body. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO19841 | ANKRD34A Knockout cell line (HeLa) | Human | ANKRD34A | 1:3~1:6 | Negative | Online Inquiry |
KO19842 | ANKRD34A Knockout cell line (HEK293) | Human | ANKRD34A | 1:3~1:6 | Negative | Online Inquiry |
ANKRD34A Gene Knockout Cell Lines are highly specialized cellular models engineered to enable the functional study of the ANKRD34A gene, which encodes an ankyrin repeat domain-containing protein implicated in various cellular processes, including signal transduction and cytoskeletal organization. These cell lines utilize CRISPR-Cas9 technology to induce precise deletions in the ANKRD34A gene, providing researchers with a robust tool to explore the biological role of this gene and its involvement in diseases, particularly cancer and neurodegenerative disorders.
The fundamental mechanism behind these knockout cell lines involves targeted genome editing, where the CRISPR system creates double-strand breaks at specific loci of the ANKRD34A gene, leading to insertions or deletions during the repair process that disrupt gene function. This allows for the effective study of loss-of-function phenotypes associated with ANKRD34A and facilitates the investigation of downstream signaling pathways.
The scientific importance of ANKRD34A Gene Knockout Cell Lines is underscored by their application in both basic research and clinical settings. They serve as vital models for drug discovery, toxicology studies, and mechanistic investigations, allowing scientists to elucidate the function of this gene in a controlled environment and unravel its role in complex biological pathways.
Compared to conventional models, such as wild-type cell lines, the ANKRD34A knockout versions offer the major advantage of specificity and reliability in studying gene function without the confounding effects of normal gene expression. This precision makes them indispensable for accurate assays in functional genomics.
Researchers and clinicians can significantly benefit from these cell lines as they provide a means to develop targeted therapies, validate biomarkers, and facilitate translational research efforts aimed at combatting diseases associated with ANKRD34A. The enhanced understanding of this gene's role can lead to novel therapeutic strategies, ultimately advancing patient care.
Our company specializes in cutting-edge genomic technologies and is dedicated to providing high-quality research tools that empower scientific advancement. With extensive expertise in gene editing technologies, we support researchers in their quest to unlock the complexities of biological systems through innovative products like the ANKRD34A Gene Knockout Cell Lines.
Please note that all services are for research use only. Not intended for any clinical use.
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