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ANKRD2 Knockout Cell Lines

Gene: ANKRD2

Official Full Name: ankyrin repeat domain 2provided by HGNC

Gene Summary: This gene encodes a protein that belongs to the muscle ankyrin repeat protein (MARP) family. A similar gene in rodents is a component of a muscle stress response pathway and plays a role in the stretch-response associated with slow muscle function. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO28137 ANKRD2 Knockout cell line (A549) Human ANKRD2 1:3~1:4 Negative Online Inquiry

Background

ANKRD2 Gene Knockout Cell Lines represent a pivotal resource in molecular biology, specifically tailored for investigating the role of the ANKRD2 gene in cellular processes. Gene knockout cell lines are engineered to have a specific gene inactivated, allowing researchers to study the phenotypic effects of eliminating that gene's function. The ANKRD2 protein is known to be involved in cardiac muscle function and signaling pathways, making these knockout cell lines invaluable for elucidating biological functions, disease mechanisms, and therapeutic targets.

The key function of ANKRD2 Gene Knockout Cell Lines lies in their ability to mimic specific pathophysiological states. By observing the cellular behavior in these lines, researchers can dissect the molecular pathways that are disrupted in the absence of ANKRD2, thus providing insights into associated disease mechanisms, particularly those related to heart disease and muscle development. The mechanism of action is based on CRISPR/Cas9 technology, ensuring a precise and efficient gene knockout that leads to a strong and reproducible phenotype.

In terms of scientific importance, ANKRD2 Gene Knockout Cell Lines serve as a critical platform for drug discovery and development, allowing for high-throughput screening of therapeutic agents that could target abnormalities stemming from ANKRD2 loss of function. In clinical settings, understanding the implications of ANKRD2 gene alterations can pave the way for personalized treatment strategies, especially in cardiomyopathies.

Compared to alternative models, such as wild-type cells or less specific gene-editing approaches, our ANKRD2 Gene Knockout Cell Lines provide a more reliable and targeted study of the gene's function. This specificity can lead to clearer, more interpretable results, driving forward the understanding of complex biological systems.

Researchers and clinicians alike will find these cell lines to be valuable in both their basic science investigations and translational research endeavors. Our expertise in developing high-quality biological products ensures that you receive not only a robust research tool but also one that is backed by scientific rigor.

At [Your Company Name], we are committed to providing cutting-edge research tools that empower scientists to unlock the mysteries of biology, with a focus on innovation and quality assurance in every product we offer.

Please note that all services are for research use only. Not intended for any clinical use.

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