Gene: ANKRD13D
Official Full Name: ankyrin repeat domain 13Dprovided by HGNC
Gene Summary: The protein encoded by this gene is a member of the ankyrin repeat domain (ANKRD) 13 family, which currently consists of four proteins containing ubiquitin-interacting motifs. These proteins are integral membrane proteins that bind specifically to Lys-63-linked ubiquitin chains on membrane-bound proteins, targeting those proteins for rapid internalization. [provided by RefSeq, Dec 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO19851 | ANKRD13D Knockout cell line (HeLa) | Human | ANKRD13D | 1:3~1:6 | Negative | Online Inquiry |
KO19852 | ANKRD13D Knockout cell line (HCT 116) | Human | ANKRD13D | 1:2~1:4 | Negative | Online Inquiry |
KO19853 | ANKRD13D Knockout cell line (HEK293) | Human | ANKRD13D | 1:3~1:6 | Negative | Online Inquiry |
KO19854 | ANKRD13D Knockout cell line (A549) | Human | ANKRD13D | 1:3~1:4 | Negative | Online Inquiry |
ANKRD13D Gene Knockout Cell Lines represent a pioneering advancement in the field of genetic research and cellular biology. These specially engineered cell lines have been developed to silence the expression of the ANKRD13D gene, thereby facilitating the study of its physiological functions and contributions to various biological processes. By utilizing CRISPR-Cas9 gene editing technology, these knockout cell lines allow researchers to create precise models that can elucidate the role of ANKRD13D in cellular activities, such as endocytosis and cellular signaling pathways.
The primary function of the ANKRD13D knockout cell lines is to provide a platform for investigating the consequences of ANKRD13D gene disruption on cell behavior and morphology. Researchers can analyze alterations in protein interactions, signaling cascades, and overall cellular dynamics that arise from the absence of this gene. This tool is particularly valuable for dissecting the molecular mechanisms underlying diseases in which ANKRD13D may play a critical role, such as cancer or neurodegenerative disorders.
The scientific importance of these cell lines extends beyond basic research; they are invaluable in drug discovery and therapeutic development, as they can be used to assess the efficacy of new treatments targeting pathways influenced by ANKRD13D. Organizations and researchers aiming to validate their hypotheses in a robust scientific setting will find these knockout cell lines particularly advantageous, as they are specifically tailored for high reproducibility and consistency in experimental results.
Unlike conventional models, the ANKRD13D knockout cell lines provide a distinct advantage by allowing for focused investigations with minimized off-target effects, ensuring that data derived from experiments remain reliable and directly attributable to the loss of ANKRD13D function. Furthermore, these cell lines are compatible with various cellular assays, including pharmacological testing and genetic rescue experiments, further enhancing their utility.
As a leading provider of innovative biological products, our company is committed to delivering high-quality tools that empower researchers and clinicians alike. With a dedication to advancing scientific discovery, the ANKRD13D Gene Knockout Cell Lines are an essential addition to any laboratory seeking to push the boundaries of genetic research.
Please note that all services are for research use only. Not intended for any clinical use.
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