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AIFM3 Knockout Cell Lines

Gene: AIFM3

Official Full Name: AIF family member 3provided by HGNC

Gene Summary: Predicted to enable oxidoreductase activity, acting on NAD(P)H. Involved in execution phase of apoptosis. Located in cytosol; endoplasmic reticulum; and mitochondrial inner membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00054 AIFM3 Knockout cell line (293T) Human AIFM3 1:3~1:6 Negative Online Inquiry
KO22120 AIFM3 Knockout cell line (HCT 116) Human AIFM3 1:2~1:4 Negative Online Inquiry
KO22121 AIFM3 Knockout cell line (A549) Human AIFM3 1:3~1:4 Negative Online Inquiry

Background

AIFM3 Gene Knockout Cell Lines are a pivotal tool in genetic research, providing researchers with a method to study the role and function of the AIFM3 gene, which is implicated in various biological processes including apoptosis and cellular response to stress. These engineered cell lines are developed through the application of CRISPR-Cas9 gene-editing technology, resulting in the elimination of AIFM3 expression. This precise modification allows scientists to dissect the gene's contributions to cellular mechanics and its potential connections to diseases, such as cancer and neurodegeneration.

The primary function of AIFM3 Gene Knockout Cell Lines lies in their ability to serve as a comparative framework for understanding gene function. By evaluating the cellular phenotype and molecular pathways in AIFM3-deficient contexts, researchers can gain valuable insights into how AIFM3 interacts with other cellular components, thereby advancing knowledge in apoptosis, inflammation, and metabolic regulation. This facilitates the identification of potential therapeutic targets, enhancing the application of these cell lines in drug discovery and development.

The scientific importance of these cell lines is underscored by their utility across various research domains, particularly in elucidating the roles of genes associated with critical pathways involved in disease processes. Researchers can utilize these knockout lines for validation studies, functional assays, and screening applications, making them an invaluable asset in both academic and clinical research environments.

Compared to traditional knockdown techniques, AIFM3 Gene Knockout Cell Lines offer a permanent genetic alteration, ensuring stable and reproducible results without the variability that can accompany transient transfections. This permanence enhances the reliability of experimental outcomes and ensures a more profound understanding of AIFM3 biology.

For researchers and clinicians seeking to explore the nuances of gene function and its implications in health and disease, AIFM3 Gene Knockout Cell Lines present a valuable opportunity to advance their projects with precision and reliability. Our company, a leader in genetic engineering technologies, is committed to providing cutting-edge biological products that empower scientists and healthcare professionals in their quest for discovery and innovation. With our expertise in the development and support of these advanced tools, we aim to assist researchers in translating their findings into impactful clinical applications.

Please note that all services are for research use only. Not intended for any clinical use.

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