Gene: ACOT13
Official Full Name: acyl-CoA thioesterase 13provided by HGNC
Gene Summary: This gene encodes a member of the thioesterase superfamily. In humans, the protein co-localizes with microtubules and is essential for sustained cell proliferation. The orthologous mouse protein forms a homotetramer and is associated with mitochondria. The mouse protein functions as a medium- and long-chain acyl-CoA thioesterase. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO20046 | ACOT13 Knockout cell line (HeLa) | Human | ACOT13 | 1:3~1:6 | Negative | Online Inquiry |
KO20047 | ACOT13 Knockout cell line (HCT 116) | Human | ACOT13 | 1:2~1:4 | Negative | Online Inquiry |
KO20048 | ACOT13 Knockout cell line (HEK293) | Human | ACOT13 | 1:3~1:6 | Negative | Online Inquiry |
KO20049 | ACOT13 Knockout cell line (A549) | Human | ACOT13 | 1:3~1:4 | Negative | Online Inquiry |
ACOT13 Gene Knockout Cell Lines are genetically engineered cell lines specifically altered to lack the expression of the ACOT13 gene, known for its role in regulating fatty acid metabolism. These knockout cell lines provide a unique model for investigating the functional implications of ACOT13 depletion in cellular processes, enabling researchers to explore its contribution to metabolic pathways, lipid homeostasis, and energy balance.
The mechanism underlying the utility of ACOT13 Gene Knockout Cell Lines lies in their ability to mimic the loss-of-function scenario associated with certain metabolic disorders. By eliminating ACOT13, these cell lines facilitate the study of subsequent physiological and biochemical alterations, thereby allowing for the exploration of compensatory mechanisms in cellular metabolism. Researchers can examine key endpoints such as fatty acid uptake, oxidation rates, and overall cell proliferation, which may yield valuable insights into diseases related to lipid metabolism, such as obesity and type 2 diabetes.
The scientific significance of ACOT13 Gene Knockout Cell Lines extends into both research and clinical applications. They serve as essential tools in the field of metabolic research, enabling the identification of novel therapeutic targets and the evaluation of potential drug candidates that could mitigate the effects of altered fatty acid metabolism. Furthermore, their usage can provide predictive data relevant to patient responses in precision medicine scenarios.
What sets ACOT13 Gene Knockout Cell Lines apart from other available models is their specificity and robustness. Unlike broader general knockouts or less targeted approaches, these cell lines offer a precise elimination of the ACOT13 gene, ensuring researchers can draw clearer conclusions regarding its physiological roles. This specificity minimizes off-target effects, enhancing data reliability.
By investing in ACOT13 Gene Knockout Cell Lines, researchers and clinicians gain invaluable tools for advancing their understanding of metabolic diseases and developing new therapeutic strategies. Our company prides itself on its commitment to providing high-quality, precisely engineered biological products, catering to the complex needs of the scientific community.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.