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ACBD4 Knockout Cell Lines

Gene: ACBD4

Official Full Name: acyl-CoA binding domain containing 4provided by HGNC

Gene Summary: This gene encodes a member of the acyl-coenzyme A binding domain containing protein family. All family members contain the conserved acyl-Coenzyme A binding domain, which binds acyl-CoA thiol esters. They are thought to play roles in acyl-CoA dependent lipid metabolism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO20056 ACBD4 Knockout cell line (HeLa) Human ACBD4 1:3~1:6 Negative Online Inquiry
KO20057 ACBD4 Knockout cell line (HCT 116) Human ACBD4 1:2~1:4 Negative Online Inquiry
KO20058 ACBD4 Knockout cell line (HEK293) Human ACBD4 1:3~1:6 Negative Online Inquiry
KO20059 ACBD4 Knockout cell line (A549) Human ACBD4 1:3~1:4 Negative Online Inquiry

Background

ACBD4 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to lack the ACBD4 gene, which encodes a protein involved in intracellular lipid transport and various cellular processes. These knockout models enable researchers to elucidate the gene's role in diverse biological pathways and disease mechanisms. By systematically deactivating the ACBD4 gene, these cell lines provide a unique framework for studying lipid metabolism, signal transduction, and other critical cellular functions.

The primary mechanism through which ACBD4 knockout cell lines operate is the absence of the ACBD4 protein, resulting in altered lipid handling and cellular responses. This disruption allows for the investigation of the protein's involvement in cellular processes such as membrane trafficking, organelle communication, and metabolic regulation. Researchers can utilize these cell lines in various experiments to highlight the impact of ACBD4 deletion on cell proliferation, apoptosis, and response to stress stimuli, thus unlocking new avenues for understanding metabolic disorders and cancer biology.

The scientific significance of ACBD4 Gene Knockout Cell Lines extends to their applications in both research and clinical settings. They serve as valuable tools for pharmaceutical companies and academic laboratories, facilitating drug discovery efforts aimed at targeting lipid-related pathways. Furthermore, these knockout models can be instrumental in identifying potential therapeutic strategies for diseases linked to lipid dysregulation, such as obesity, diabetes, and non-alcoholic fatty liver disease.

What sets ACBD4 Gene Knockout Cell Lines apart from alternative models is their precision and specificity in gene alteration. Unlike traditional methods, these cell lines offer a reproducible and controlled environment for experiments, reducing variability and enhancing the reliability of results. Additionally, they are compatible with a wide range of assays, including gene expression analysis, protein interaction studies, and high-throughput screening, thus broadening their utility in diverse research communities.

For researchers and clinicians seeking innovative solutions in gene function analysis and therapeutic development, ACBD4 Gene Knockout Cell Lines present a compelling opportunity. They empower studies that may lead to groundbreaking discoveries in disease mechanisms and treatment options, ultimately contributing to enhanced patient care.

At [Your Company Name], we pride ourselves on our longstanding expertise in creating high-quality genetic tools that facilitate advanced biological research. Our commitment to scientific excellence ensures that our products meet the rigorous standards of the research community, advancing knowledge and innovation in the life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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