Gene: ACAD11
Official Full Name: acyl-CoA dehydrogenase family member 11provided by HGNC
Gene Summary: This gene encodes an acyl-CoA dehydrogenase enzyme with a preference for carbon chain lengths between 20 and 26. Naturally occurring read-through transcription occurs between the upstream gene NPHP3 (nephronophthisis 3 (adolescent)) and this gene. [provided by RefSeq, Aug 2015]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO25175 | ACAD11 Knockout cell line (HeLa) | Human | ACAD11 | 1:3~1:6 | Negative | Online Inquiry |
KO25176 | ACAD11 Knockout cell line (HCT 116) | Human | ACAD11 | 1:2~1:4 | Negative | Online Inquiry |
KO25177 | ACAD11 Knockout cell line (HEK293) | Human | ACAD11 | 1:3~1:6 | Negative | Online Inquiry |
KO25178 | ACAD11 Knockout cell line (A549) | Human | ACAD11 | 1:3~1:4 | Negative | Online Inquiry |
ACAD11 Gene Knockout Cell Lines are specialized cellular models designed for the in-depth study of the ACAD11 gene, which encodes an enzyme involved in fatty acid metabolism. These knockout cell lines are engineered to have the ACAD11 gene inactivated, thus providing a powerful tool for researchers to dissect the biological roles and metabolic pathways influenced by this gene. By studying these cells, scientists can gain insights into the molecular mechanisms underlying metabolic disorders, such as obesity and insulin resistance, and assess the gene's influence on lipid profiles and energy homeostasis.
The key function of ACAD11 gene knockout cell lines lies in their ability to mimic the physiological conditions of cells lacking functional ACAD11. This is achieved through advanced gene-editing techniques, such as CRISPR-Cas9, which allow for precise modifications of the cellular genome. As a result, these lines facilitate the assessment of gene function, enabling researchers to investigate the downstream effects of ACAD11 deficiency on cellular metabolism and signaling pathways.
The scientific importance of these cell lines is underscored by their broad applications in both fundamental research and clinical settings. They can serve as models to evaluate potential therapeutic interventions, such as small-molecule drugs or gene therapies, aimed at correcting metabolic dysregulation associated with ACAD11 dysfunction. Moreover, by employing these knockout cell lines, researchers can conduct high-throughput screening to identify novel compounds that modulate metabolic pathways.
One of the unique selling points of the ACAD11 Gene Knockout Cell Lines is their specific focus on a critical gene linked to metabolism, which is often less explored compared to other metabolic genes. This specificity provides researchers with valuable insights that are difficult to obtain from more generic models. Additionally, these cell lines undergo rigorous validation processes to ensure consistent performance and reproducibility, which enhances the reliability of experimental outcomes.
For researchers and clinicians seeking to deepen their understanding of metabolic processes, ACAD11 Gene Knockout Cell Lines are an indispensable resource that facilitates innovative studies aimed at combating metabolic disorders. This product embodies our commitment to providing high-quality, cutting-edge biological tools that leverage our expertise in genetics and cellular biology, empowering scientists to advance their research and contribute to breakthroughs in health and medicine.
Please note that all services are for research use only. Not intended for any clinical use.
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