Gene: ABITRAM
Official Full Name: actin binding transcription modulatorprovided by HGNC
Gene Summary: Predicted to enable actin filament binding activity and actin monomer binding activity. Predicted to be involved in dendrite morphogenesis; regulation of actin filament polymerization; and regulation of filopodium assembly. Predicted to be located in growth cone. Predicted to be active in several cellular components, including dendrite; filopodium tip; and lamellipodium. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO20071 | ABITRAM Knockout cell line (HeLa) | Human | ABITRAM | 1:3~1:6 | Negative | Online Inquiry |
KO20072 | ABITRAM Knockout cell line (HCT 116) | Human | ABITRAM | 1:2~1:4 | Negative | Online Inquiry |
KO20073 | ABITRAM Knockout cell line (HEK293) | Human | ABITRAM | 1:3~1:6 | Negative | Online Inquiry |
KO20074 | ABITRAM Knockout cell line (A549) | Human | ABITRAM | 1:3~1:4 | Negative | Online Inquiry |
ABITRAM Gene Knockout Cell Lines are meticulously engineered cellular models designed for advanced functional genomics studies, where specific genes are intentionally disrupted to elucidate their roles in biological processes. These cell lines allow researchers to investigate gene function, signaling pathways, and cellular responses, providing a powerful tool for dissecting molecular mechanisms underlying diseases.
The key functions of ABITRAM Gene Knockout Cell Lines arise from their ability to generate precise gene deletions using CRISPR-Cas9 technology. This innovative approach ensures high efficiency and specificity in gene targeting, facilitating robust validation of gene functions. Once created, these knockout cell lines exhibit phenotypic changes reflecting the loss of function of the targeted gene, enabling comprehensive assessments in various experimental settings, from drug discovery to toxicology.
Scientifically, these cell lines hold significant importance in both research and clinical applications. They are instrumental in functional studies for cancer research, developmental biology, and neurobiology, allowing scientists to model and understand complex diseases better. The ability to consistently reproduce gene knockout events fosters reproducibility and reliability in experimental outcomes, thereby accelerating the pace of discovery.
Compared to traditional gene knockdown methods like siRNA or shRNA, ABITRAM Gene Knockout Cell Lines offer superior stability and permanence in gene silencing, making them ideal for long-term studies. Additionally, the high scalability of these cell lines permits their use across various species and cell types, providing unprecedented versatility in research applications.
For researchers and clinicians, the adoption of ABITRAM Gene Knockout Cell Lines can lead to pioneering discoveries, improved therapeutic strategies, and enhanced understanding of genetic contributions to disease. Their reliable performance and comprehensive support serve as invaluable assets for advancing scientific inquiry.
Backed by our extensive expertise in genetic engineering and cell biology, our company is dedicated to providing high-quality biological products that empower the life sciences community to push the boundaries of research and therapeutic development.
Please note that all services are for research use only. Not intended for any clinical use.
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