Gene: ABHD11
Official Full Name: abhydrolase domain containing 11provided by HGNC
Gene Summary: This gene encodes a protein containing an alpha/beta hydrolase fold domain. This gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. [provided by RefSeq, Mar 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO25502 | ABHD11 Knockout cell line (HeLa) | Human | ABHD11 | 1:3~1:6 | Negative | Online Inquiry |
KO25503 | ABHD11 Knockout cell line (HCT 116) | Human | ABHD11 | 1:2~1:4 | Negative | Online Inquiry |
KO25504 | ABHD11 Knockout cell line (HEK293) | Human | ABHD11 | 1:3~1:6 | Negative | Online Inquiry |
ABHD11 Gene Knockout Cell Lines are genetically engineered cellular models designed to specifically disrupt the expression of the Abhydrolase Domain Containing 11 (ABHD11) gene. This gene encodes an enzyme implicated in lipid metabolism and signaling pathways, making it a pivotal target for studies involving metabolic disorders, inflammation, and neurobiology. By removing the function of ABHD11, these knockout cell lines allow researchers to investigate the downstream effects of its absence, providing insights into cellular mechanisms that influence disease states.
The key functionality of the ABHD11 Gene Knockout Cell Lines lies in their ability to facilitate the study of gene function and its physiological roles. Through techniques such as CRISPR-Cas9, these cell lines are precisely altered to lack ABHD11, thus enabling scientists to explore the biochemical and cellular pathways affected by this gene. Researchers can analyze changes in lipid profiles, signaling cascades, and cellular responses to various stimuli, deepening the understanding of ABHD11's contribution to fundamental biological processes.
From a scientific perspective, ABHD11 Gene Knockout Cell Lines hold great importance in both research and clinical settings, particularly in the realms of metabolic regulation and neurodegenerative diseases. Their application can lead to novel therapeutic strategies targeting ABHD11-related pathways, thereby advancing treatment options for conditions such as obesity, diabetes, and neuroinflammation.
Compared to traditional cell lines that express ABHD11, these knockout models provide a unique advantage by offering a controlled environment to study the effects of gene loss without confounding influences. This specificity allows for more accurate data collection and interpretation, critical in the pursuit of reproducible scientific results.
For researchers and clinicians, the value of ABHD11 Gene Knockout Cell Lines lies in their ability to enhance the understanding of complex biological systems and inform the development of targeted therapeutics. The discerning scientist can leverage these models to unlock new discoveries that can translate into meaningful clinical advancements.
Our company specializes in the development and provision of cutting-edge biological products, ensuring that our offerings, including the ABHD11 Gene Knockout Cell Lines, are of the highest quality and supported by extensive scientific expertise.
Please note that all services are for research use only. Not intended for any clinical use.
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