CYFIP1 Knockout cell line (NCM460)

Catalog Number: KOA72463

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Specifications

Product Information
Product Name	CYFIP1 Knockout cell line (NCM460)
specification	1*10^6
Storage and transportation	Shipped on dry ice; Store in liquid nitrogen
Cell morphology	Epithelial-like, adheren
Passage ratio	1:2~1:3
species	Human
Gene	CYFIP1
Gene ID	23191
Build method	Electroporation/Lentivirus
Mycoplasma testing	negative
Cultivation system	90%RPMI-1640+10%FBS
Parental Cell Line	NCM460
Quality Control	Genotype: CYFIP1 Knockout cell line (NCM460)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.

Gene Information
Gene Official Full Name	cytoplasmic FMR1 interacting protein 1provided by HGNC
Also known as	SHYC; SRA1; SRA-1; P140SRA-1
Gene Description	This gene encodes a protein that regulates cytoskeletal dynamics and protein translation. The encoded protein is a component of the WAVE regulatory complex (WRC), which promotes actin polymerization. This protein also interacts with the synaptic functional regulator FMR1 protein and translation initiation factor 4E to inhibit protein translation. A large chromosomal deletion including this gene is associated with increased risk of schizophrenia and epilepsy in human patients. Reduced expression of this gene has been observed in various human cancers and the encoded protein may inhibit tumor invasion. [provided by RefSeq, Mar 2022]
Expression	Ubiquitous expression in placenta (RPKM 24.8), esophagus (RPKM 20.9) and 25 other tissues See more

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