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PMS1 Knockout cell line (HeLa)

Catalog Number: KO06226

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Specifications

Product Information
Product Name PMS1 Knockout cell line (HeLa)
specification 1*10^6
Storage and transportation Dry ice preservation/T25 live cell transportation.
Cell morphology Epithelioid, adherent cell
Passage ratio 1:3~1:6
species Human
Gene PMS1
Gene ID 5378
Build method Electric rotation method / virus method
Mycoplasma testing Negative
Cultivation system 90%DMEM+10% FBS
Parental Cell Line HeLa
Quality Control Genotype: PMS1 Knockout cell line (HeLa) >95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.
Gene Information
Gene Official Full Name PMS1 homolog 1, mismatch repair system componentprovided by HGNC
Also known as MLH2; PMSL1; hPMS1; HNPCC3
Gene Description This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome. [provided by RefSeq, Jul 2008]
Expression Ubiquitous expression in testis (RPKM 8.3), endometrium (RPKM 3.7) and 24 other tissues See more

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