PDE1A Knockout cell line (HEK293)
Catalog Number: KO07958
Price: Online Inquiry
Catalog Number: KO07958
Price: Online Inquiry
Product Information | |
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Product Name | PDE1A Knockout cell line (HEK293) |
specification | 1*10^6 |
Storage and transportation | Dry ice preservation/T25 live cell transportation. |
Cell morphology | Epithelioid, adherent cell |
Passage ratio | 1:3~1:6 |
species | Human |
Gene | PDE1A |
Gene ID | 5136 |
Build method | Electric rotation method / virus method |
Mycoplasma testing | Negative |
Cultivation system | 90%DMEM+10% FBS |
Parental Cell Line | HEK293 |
Quality Control | Genotype: PDE1A Knockout cell line (HEK293) >95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins. |
Gene Information | |
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Gene Official Full Name | phosphodiesterase 1Aprovided by HGNC |
Also known as | HCAM1; HCAM-1; HSPDE1A; CAM-PDE 1A; CAM-PDE-1A |
Gene Description | Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109]; Fidock et al., 2002 [PubMed 11747989]).[supplied by OMIM, Oct 2009] |
Expression | Broad expression in thyroid (RPKM 7.4), brain (RPKM 6.5) and 18 other tissues See more |
Please note that all services are for research use only. Not intended for any clinical use.
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