Introduction
Synthetic biology involves engineering biological systems through the design and construction of new biological parts, devices, and systems, or the modification of existing ones. One of the key challenges in synthetic biology is to create efficient and reliable metabolic pathways in microbial strains.
Metabolic throughout analysis is a powerful tool for understanding the metabolic pathways of microorganisms under different conditions. CD Biosynsis will help to understand the importance of metabolic throughout analysis in synthetic biology strains and accelarete the research in this field.
Figure 1: Time-resolved extracellular metabolite concentrations (mmol/l) of COL and HG001 were visualized with MeV as color coded chart. (Dörries K, Lalk M. 2013)
Our Services for Metabolic Throughout Analysis
At CD Biosynsis, we offer a range of services for metabolic throughout analysis in synthetic biology strains. Our services include:
High-Throughput Metabolomics
We use high-throughput metabolomics techniques such as
--Fourier transform infrared spectroscopy (FT-IR)
--gas chromatography mass spectrometry (GC-MS)
to analyze the metabolic pathways of microorganisms under different conditions. These techniques enable us to identify metabolites and pathways that are affected by changes in environmental conditions, genetic modifications, or other factors.
Metabolic Flux Analysis
Metabolic flux analysis (MFA) is a powerful tool for understanding the metabolic pathways of microorganisms. We use MFA to quantify the fluxes of metabolites through different pathways in synthetic biology strains. This enables us to identify key metabolic bottlenecks and optimize metabolic pathways to improve the efficiency of microbial strains.
Isotope Tracing
Isotope tracing is a powerful method for understanding the dynamics of metabolic pathways in microbial strains. We use isotope tracing to track the fate of isotopically labeled metabolites in synthetic biology strains. This enables us to identify the fluxes of metabolites through different pathways and determine the efficiency of metabolic pathways.
Data Analysis and Interpretation
We provide comprehensive data analysis and interpretation services for metabolic throughout analysis in synthetic biology strains. Our team of experts uses advanced statistical and bioinformatics tools to analyze the data generated from metabolomics, MFA, and isotope tracing experiments.
We provide detailed reports and recommendations for optimizing metabolic pathways in microbial strains.
Our Advantages
At CD Biosynsis, we have years of experience in the field of synthetic biology and metabolic throughout analysis. We offer several advantages over other companies in the field:
Customized Solutions
We provide customized solutions for metabolic throughout analysis based on the specific needs of our clients.
Advanced Analytical Techniques
We use advanced analytical techniques such as FT-IR, GC-MS, and isotope tracing to analyze the metabolic pathways of microorganisms.
Comprehensive Data Analysis
We provide comprehensive data analysis and interpretation services for metabolic throughout analysis. Our team of experts uses advanced statistical and bioinformatics tools to analyze the data generated from metabolomics, MFA, and isotope tracing experiments.
Fast Turnaround Time
We understand the importance of timely results in synthetic biology research. We offer fast turnaround times for our services, enabling our clients to move quickly from experimental design to data analysis and interpretation.
Metabolic throughout analysis is a powerful tool for understanding the metabolic pathways of microorganisms in synthetic biology strains. CD Biosynsis offers a range of services for metabolic throughout analysis, including high-throughput metabolomics, metabolic flux analysis, isotope tracing, and data analysis and interpretation. Our customized solutions and other advantages make us the ideal partner for metabolic throughout analysis in synthetic biology strains.
Contact us today to learn more about our services and how we can help you optimize your metabolic throughout analysis.
References
- Dörries K, Lalk M. Metabolic footprint analysis uncovers strain specific overflow metabolism and D-isoleucine production of Staphylococcus aureus COL and HG001. PLoS One. 2013; 8(12): e81500 (2013). doi:10.1371/journal.pone.0081500.
- Carlson, R., Fell, D. et al. Metabolic pathway analysis of a recombinant yeast for rational strain development. Biotechnology and Bioengineering, 79: 121-134 (2002). https://doi.org/10.1002/bit.10305
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