CTSK Knockout cell line (NCM460)
Catalog Number: KOA78023
Price: Online Inquiry
Catalog Number: KOA78023
Price: Online Inquiry
| Product Information | |
|---|---|
| Product Name | CTSK Knockout cell line (NCM460) |
| specification | 1*10^6 |
| Storage and transportation | Shipped on dry ice; Store in liquid nitrogen |
| Cell morphology | Epithelial-like, adheren |
| Passage ratio | 1:2~1:3 |
| species | Human |
| Gene | CTSK |
| Gene ID | 1513 |
| Build method | Electroporation/Lentivirus |
| Mycoplasma testing | negative |
| Cultivation system | 90%RPMI-1640+10%FBS |
| Parental Cell Line | NCM460 |
| Quality Control | Genotype: CTSK Knockout cell line (NCM460)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins. |
| Gene Information | |
|---|---|
| Gene Official Full Name | cathepsin Kprovided by HGNC |
| Also known as | CTSO; PKND; PYCD; CTS02; CTSO1; CTSO2 |
| Gene Description | The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. [provided by RefSeq, Apr 2013] |
| Expression | Broad expression in gall bladder (RPKM 190.4), urinary bladder (RPKM 132.0) and 15 other tissues See more |
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