DOCK8 Knockout cell line (U-2932)

Catalog Number: KOA37624

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Specifications

Product Information
Product Name	DOCK8 Knockout cell line (U-2932)
specification	1*10^6
Storage and transportation	Shipped on dry ice; Store in liquid nitrogen
Cell morphology	Human Lymphocyte-like, suspension
Passage ratio	1：2-1：4
species	Human
Gene	DOCK8
Gene ID	81704
Build method	Electroporation/Lentivirus
Mycoplasma testing	negative
Cultivation system	90%RPMI-1640+10%FBS
Parental Cell Line	U-2932
Quality Control	Genotype: DOCK8 Knockout cell line (U-2932)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.

Gene Information
Gene Official Full Name	dedicator of cytokinesis 8provided by HGNC
Also known as	MRD2; ZIR8; HIES2; HEL-205
Gene Description	This gene encodes a member of the DOCK180 family of guanine nucleotide exchange factors. Guanine nucleotide exchange factors interact with Rho GTPases and are components of intracellular signaling networks. Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Jun 2010]
Expression	Broad expression in lymph node (RPKM 24.2), spleen (RPKM 23.1) and 21 other tissues See more

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