DES Knockout cell line (NCM460)

Catalog Number: KOA77931

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Specifications

Product Information
Product Name	DES Knockout cell line (NCM460)
specification	1*10^6
Storage and transportation	Shipped on dry ice; Store in liquid nitrogen
Cell morphology	Epithelial-like, adheren
Passage ratio	1:2~1:3
species	Human
Gene	DES
Gene ID	1674
Build method	Electroporation/Lentivirus
Mycoplasma testing	negative
Cultivation system	90%RPMI-1640+10%FBS
Parental Cell Line	NCM460
Quality Control	Genotype: DES Knockout cell line (NCM460)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.

Gene Information
Gene Official Full Name	desminprovided by HGNC
Also known as	CSM1; CSM2; CDCD3; LGMD1D; LGMD1E; LGMD2R
Gene Description	This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. [provided by RefSeq, Jul 2008]
Expression	Biased expression in heart (RPKM 2605.8), esophagus (RPKM 953.7) and 6 other tissues See more

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