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ARAP1 Knockout cell line (HCT 116)

Catalog Number: KO30474

Price: Online Inquiry

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Specifications

Product Information
Product Name ARAP1 Knockout cell line (HCT 116)
specification 1*10^6
Storage and transportation Dry ice preservation/T25 live cell transportation.
Cell morphology Epithelioid, adherent cell
Passage ratio 1:2~1:4
species Human
Gene ARAP1
Gene ID 116985
Build method Electric rotation method / virus method
Mycoplasma testing Negative
Cultivation system 90%McCOYs 5A+10% FBS
Parental Cell Line HCT 116
Quality Control Genotype: ARAP1 Knockout cell line (HCT 116) >95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.
Gene Information
Gene Official Full Name ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1provided by HGNC
Also known as CENTD2; cnt-d2
Gene Description The protein encoded by this gene contains SAM, ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology (PH) domains. In vitro, this protein displays RHO-GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3)-dependent ARF-GAP activity. The encoded protein associates with the Golgi, and the ARF-GAP activity mediates changes in the Golgi and the formation of filopodia. It is thought to regulate the cell-specific trafficking of a receptor protein involved in apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
Expression Ubiquitous expression in spleen (RPKM 32.0), appendix (RPKM 25.3) and 25 other tissues See more

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