Gene: ZNF846
Official Full Name: zinc finger protein 846provided by HGNC
Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO11937 | ZNF846 Knockout cell line (HeLa) | Human | ZNF846 | 1:3~1:6 | Negative | Online Inquiry |
KO11938 | ZNF846 Knockout cell line (HEK293) | Human | ZNF846 | 1:3~1:6 | Negative | Online Inquiry |
KO11939 | ZNF846 Knockout cell line (A549) | Human | ZNF846 | 1:3~1:4 | Negative | Online Inquiry |
ZNF846 Gene Knockout Cell Lines are precisely engineered cellular models designed to facilitate the study of the ZNF846 gene and its associated functions. By utilizing the CRISPR-Cas9 gene-editing technology, these cell lines have been developed to create a complete knockout of the ZNF846 gene, enabling researchers to investigate the gene's role in various biological processes and pathologies.
The primary mechanism through which ZNF846 knockout cell lines operate is by disrupting the genomic sequence of the ZNF846 gene, effectively eliminating its expression. This allows scientists to observe cellular changes, signaling pathways, and phenotypic alterations that occur as a direct consequence of ZNF846 deficiency. Such insights are crucial for understanding the gene's contributions to specific metabolic pathways, cellular functions, and potential implications in disease states, particularly in cancer and neurodegenerative disorders.
The scientific significance of ZNF846 knockout cell lines extends into both research and clinical applications. For example, these cell lines provide invaluable tools for drug screening, target validation, and functional genomics studies. Researchers can utilize these models to assess the impact of therapeutic agents on cell behavior in the absence of ZNF846, thus paving the way for novel treatment strategies.
One of the key advantages of ZNF846 knockout cell lines lies in their specificity and reliability. Unlike conventional gene silencing methods that may yield varying results due to incomplete knockdown, CRISPR-mediated knockout ensures a robust and consistent gene disruption. This precision enhances the reproducibility of experimental results, a critical factor for researchers seeking reliable outcomes in their studies.
Additionally, the ZNF846 gene knockout cell lines are versatile and can be adapted for various research applications, making them vital resources for laboratories focused on genetic research and developmental biology. Researchers, clinicians, and industry professionals will find these cell lines immensely valuable, as they foster deeper understanding and innovative solutions in the field of genetics.
By choosing our ZNF846 Gene Knockout Cell Lines, users are benefiting from our company's extensive expertise in developing cutting-edge biological products. We are committed to delivering high-quality, scientifically validated tools that empower researchers in their quest for knowledge and advancements in health science.
Please note that all services are for research use only. Not intended for any clinical use.
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