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ZNF83 Knockout Cell Lines

Gene: ZNF83

Official Full Name: zinc finger protein 83provided by HGNC

Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00053 ZNF83 Knockout cell line (786-O) Human ZNF83 Negative Online Inquiry

Background

ZNF83 Gene Knockout Cell Lines represent a highly specialized resource designed for researchers investigating the function and regulation of the ZNF83 gene, which encodes a zinc finger protein implicated in various biological processes, including gene expression modulation and cellular signaling pathways. These cell lines are expertly engineered to create a loss-of-function model for the ZNF83 gene, facilitating the study of its role in cellular mechanisms, development, and disease pathology.

The primary mechanism of action involves the targeted disruption of the ZNF83 gene through established gene editing techniques, such as CRISPR/Cas9. By producing these knockout cell lines, scientists can elucidate the gene's contribution to cellular processes and explore its interactions with other genes and proteins. This is critical for understanding its potential involvement in conditions such as cancer, autoimmune diseases, and other genetic disorders.

The scientific significance of ZNF83 Gene Knockout Cell Lines lies in their application across various research fields, including molecular biology, genetics, and pharmacology. These models provide a platform for drug discovery, enabling the identification of therapeutic targets and the assessment of drug efficacy in conditions associated with ZNF83 dysregulation.

Compared to other experimental models, such as whole-animal studies or overexpression systems, ZNF83 knockout cell lines offer a distinct advantage in terms of specificity and control. Researchers benefit from the ability to perform high-throughput screening and detailed functional assays with minimal variability, ensuring reproducibility and enhancing the reliability of results.

For researchers, clinicians, and biopharmaceutical companies, the availability of ZNF83 Gene Knockout Cell Lines presents a valuable tool for advancing their understanding of gene functions. This can lead to novel therapeutic strategies and insights into disease mechanisms. Our commitment to quality and innovation in biotechnology allows us to deliver exceptional biological products, positioning us as a trusted partner in advancing scientific research and clinical applications.

Please note that all services are for research use only. Not intended for any clinical use.

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