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ZNF467 Knockout Cell Lines

Gene: ZNF467

Official Full Name: zinc finger protein 467provided by HGNC

Gene Summary: The protein encoded by this gene is a zinc finger protein whose function has not yet been elucidated in humans. However, the mouse ortholog of this protein enhances adipocyte differentiation and suppresses osteoblast differentiation in bone marrow. The mouse protein also is a transcription factor for several genes and can help recruit histone deacetylase complexes. [provided by RefSeq, Aug 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO12213 ZNF467 Knockout cell line (HCT 116) Human ZNF467 1:2~1:4 Negative Online Inquiry
KO12214 ZNF467 Knockout cell line (A549) Human ZNF467 1:3~1:4 Negative Online Inquiry

Background

ZNF467 Gene Knockout Cell Lines are a sophisticated tool designed for molecular biology research, facilitating in-depth studies of gene function and regulation. By utilizing CRISPR/Cas9 technology, these cell lines have been engineered to silence the ZNF467 gene, which codes for a zinc finger protein iconic to transcriptional regulation. The result is a precise model that allows researchers to explore the downstream effects of ZNF467 loss on cellular processes, including differentiation, proliferation, and response to external stimuli.

The key mechanism behind the ZNF467 gene knockout involves targeted genomic alterations that disrupt the normal functioning of the gene. This disruption leads to a cascade of effects that can be observed through various biological assays, enabling the dissection of pathways and interactions in which the ZNF467 protein is involved. Such insights are pivotal for understanding diseases linked to transcriptional dysregulation, including cancer and genetic disorders.

Scientifically, these cell lines represent a significant leap in experimental capabilities, providing a reliable and reproducible model for both basic and translational research. In clinical settings, they offer avenues to evaluate potential therapeutic strategies aimed at modulating gene expression and identify biomarkers associated with ZNF467 involvement in pathology.

Compared to traditional knockout methodologies, the ZNF467 Gene Knockout Cell Lines offer superior efficiency and specificity, reducing off-target effects commonly encountered with other gene manipulation techniques. This precision ensures that experimental outcomes are robust and credible, enhancing the reliability of research findings.

For researchers and clinicians alike, these cell lines are invaluable for their capacity to elucidate the biological roles of ZNF467 in health and disease. They empower scientists to investigate complex biological questions with clarity, paving the way for innovative treatments and a deeper understanding of molecular biology.

Our company prides itself on delivering high-quality biological products backed by rigorous scientific research and expertise in gene editing technologies. We are committed to supporting the scientific community with cutting-edge tools that accelerate discovery and improve outcomes in both research and clinical applications.

Please note that all services are for research use only. Not intended for any clinical use.

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