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ZFP90 Knockout Cell Lines

Gene: ZFP90

Official Full Name: ZFP90 zinc finger proteinprovided by HGNC

Gene Summary: This gene encodes a member of the zinc finger protein family that modulates gene expression. The encoded protein derepresses the transcription of certain fetal cardiac genes and may contribute to the genetic reprogramming that occurs during the development of heart failure. Genome wide association studies have identified this gene among ulcerative colitis risk loci. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Mar 2015]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24010 ZFP90 Knockout cell line (HeLa) Human ZFP90 1:3~1:6 Negative Online Inquiry
KO24011 ZFP90 Knockout cell line (HCT 116) Human ZFP90 1:2~1:4 Negative Online Inquiry
KO24012 ZFP90 Knockout cell line (HEK293) Human ZFP90 1:3~1:6 Negative Online Inquiry
KO24013 ZFP90 Knockout cell line (A549) Human ZFP90 1:3~1:4 Negative Online Inquiry

Background

ZFP90 Gene Knockout Cell Lines are genetically modified cell lines designed to enable targeted disruption of the ZFP90 gene, which is crucial in various cellular processes, including gene regulation and stress response pathways. By utilizing CRISPR-Cas9 technology, these cell lines facilitate the precise deletion or inactivation of the ZFP90 gene, allowing researchers to investigate its specific roles in cellular physiology and pathology. This genetic knockout mechanism offers the ability to study phenotypic changes that result from the absence of ZFP90, thus providing insights into its contribution to diseases such as cancer and neurodegenerative disorders.

The key functions of ZFP90 involve its role as a transcription factor that can modulate gene expression in response to environmental signals. Understanding ZFP90's mechanisms can unravel critical insights into how cells adapt to stressors and how these pathways may be dysregulated in various diseases. In both research and clinical settings, ZFP90 Gene Knockout Cell Lines have significant implications, particularly in the context of drug discovery and the development of targeted therapies. By utilizing these knockout models, scientists can evaluate the efficacy and mechanisms of new drugs, thereby paving the way for more personalized treatments.

What sets ZFP90 Gene Knockout Cell Lines apart from alternatives, such as traditional siRNA methods, is their permanence and reliability. While siRNA-mediated knockdowns are transient and can vary between experiments, the CRISPR-Cas9-induced knockout provides a stable and heritable genetic modification, allowing for long-term studies and reproducible results. This stability is critical for high-throughput screening and longitudinal studies.

For researchers and clinicians alike, ZFP90 Gene Knockout Cell Lines deliver a powerful tool to unlock the biological roles of ZFP90, offering potential breakthroughs in understanding disease mechanisms and therapeutic interventions. These cell lines are invaluable assets for academic research, pharmaceutical development, and biotechnology ventures.

Our company boasts extensive expertise in developing high-quality gene knockout products, employing cutting-edge technologies and stringent quality control measures. We are committed to supporting the scientific community with innovative solutions like ZFP90 Gene Knockout Cell Lines that drive research forward and improve patient outcomes.

Please note that all services are for research use only. Not intended for any clinical use.

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