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XPNPEP3 Knockout Cell Lines

Gene: XPNPEP3

Official Full Name: X-prolyl aminopeptidase 3provided by HGNC

Gene Summary: The protein encoded by this gene belongs to the family of X-pro-aminopeptidases that utilize a metal cofactor, and remove the N-terminal amino acid from peptides with a proline residue in the penultimate position. This protein has been shown to localize to the mitochondria of renal cells, and have a role in ciliary function. Mutations in this gene are associated with nephronophthisis-like nephropathy-1. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene, however, expression of some of these isoforms in vivo is not known.[provided by RefSeq, Mar 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO12554 XPNPEP3 Knockout cell line (HeLa) Human XPNPEP3 1:3~1:6 Negative Online Inquiry
KO12555 XPNPEP3 Knockout cell line (HCT 116) Human XPNPEP3 1:2~1:4 Negative Online Inquiry
KO12556 XPNPEP3 Knockout cell line (HEK293) Human XPNPEP3 1:3~1:6 Negative Online Inquiry
KO12557 XPNPEP3 Knockout cell line (A549) Human XPNPEP3 1:3~1:4 Negative Online Inquiry

Background

XPNPEP3 Gene Knockout Cell Lines are specialized cell lines in which the XPNPEP3 gene has been intentionally disrupted or knocked out, providing invaluable tools for researchers studying the functional implications of this gene in various biological processes. XPNPEP3 encodes an enzyme that plays a crucial role in peptide metabolism and is implicated in the processing of bioactive peptides involved in numerous physiological responses.

The primary function of the XPNPEP3 knockout model is to enable the detailed examination of its role in immune function, cellular signaling, and metabolic pathways. By eliminating the expression of the XPNPEP3 protein, researchers can investigate downstream effects and compensatory mechanisms that might occur in its absence, facilitating a clearer understanding of its significance in health and disease.

This product holds significant scientific importance in both research and clinical settings, particularly for studies related to immune response, inflammatory diseases, and metabolic disorders. Researchers can utilize these cell lines to screen for therapeutic targets, assess drug efficacy, and unravel the molecular mechanisms underlying health conditions related to the dysfunction of peptide processing.

Compared to alternative models, XPNPEP3 Gene Knockout Cell Lines offer a specific focus on the XPNPEP3 gene, minimizing off-target effects and providing a more controlled environment for studying gene-specific pathways. This precise genetic alteration allows for high reproducibility and reliability of results, giving researchers confidence in their findings.

The value of XPNPEP3 Gene Knockout Cell Lines lies in their capacity to contribute significantly to the field of biomedical research, providing insights that could lead to novel therapeutic strategies and biomarkers. Given the growing interest in peptide-based therapies and the understanding of metabolic diseases, these cell lines are an essential resource for both academic and industrial researchers.

At [Company Name], we pride ourselves on our commitment to advancing scientific knowledge through innovative biological products. Our expertise in gene editing and cell line development fuels our mission to provide high-quality tools that empower researchers to unlock new possibilities in the life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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