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TTLL6 Knockout Cell Lines

Gene: TTLL6

Official Full Name: tubulin tyrosine ligase like 6provided by HGNC

Gene Summary: Predicted to enable tubulin binding activity and tubulin-glutamic acid ligase activity. Predicted to be involved in microtubule bundle formation; protein polyglutamylation; and regulation of cilium beat frequency involved in ciliary motility. Predicted to act upstream of or within microtubule severing and positive regulation of cilium movement. Located in ciliary basal body. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO12950 TTLL6 Knockout cell line (A549) Human TTLL6 1:3~1:4 Negative Online Inquiry

Background

TTLL6 Gene Knockout Cell Lines are specialized cellular models designed to facilitate the in-depth study of the TTLL6 gene's function and its role in cellular processes. These knockout cell lines have been meticulously engineered to ensure the complete ablation of TTLL6 expression, enabling researchers to investigate the downstream effects and compensatory mechanisms in various biological contexts. The deletion of this gene provides unique insights into its involvement in critical pathways such as microtubule dynamics, cellular motility, and signaling cascades.

The primary function of TTLL6 involves the regulation of tubulin modifications, which are crucial for maintaining cytoskeletal integrity and cellular stability. By utilizing these knockout cell lines, researchers can elucidate the cellular consequences of the absence of TTLL6, including alterations to cell morphology, migration, and division—key factors in the study of cancer biology and neurodegenerative diseases. As such, these cell lines offer a valuable tool for elucidating the molecular underpinnings of pathologies linked to cytoskeletal dysfunction.

One of the significant advantages of our TTLL6 Gene Knockout Cell Lines is their high specificity and reproducibility compared to traditional methods, such as RNA interference, which may incompletely silence gene expression or affect off-target genes. This precision allows for more accurate interpretation of experimental results and enhances the reliability of findings. Additionally, our knockout lines are validated by rigorous testing, ensuring that users can confidently shift their experimental designs without concern for genetic variability.

For researchers and clinicians involved in cell biology, developmental biology, or cancer research, TTLL6 Gene Knockout Cell Lines represent a critical asset in advancing their investigations. By leveraging these models, they can achieve clearer insights into gene functions, ultimately fostering the development of innovative therapeutic strategies.

Our company prides itself on a strong foundation in molecular biology and genetic engineering, resulting in high-quality biological products that support researchers and clinicians in their quest for knowledge and discovery. We are committed to providing robust tools that catalyze scientific advancement and empower breakthroughs in health and disease understanding.

Please note that all services are for research use only. Not intended for any clinical use.

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