Gene: TOX2
Official Full Name: TOX high mobility group box family member 2provided by HGNC
Gene Summary: Enables transcription coactivator activity. Involved in positive regulation of transcription by RNA polymerase II. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO02292 | TOX2 Knockout cell line (HeLa) | Human | TOX2 | 1:3~1:6 | Negative | Online Inquiry |
KO02293 | TOX2 Knockout cell line (HCT 116) | Human | TOX2 | 1:2~1:4 | Negative | Online Inquiry |
KO02294 | TOX2 Knockout cell line (HEK293) | Human | TOX2 | 1:3~1:6 | Negative | Online Inquiry |
KO02295 | TOX2 Knockout cell line (A549) | Human | TOX2 | 1:3~1:4 | Negative | Online Inquiry |
TOX2 Gene Knockout Cell Lines are genetically engineered cellular models that have been meticulously crafted to disable the expression of the TOX2 gene, a transcription factor involved in immune system regulation and various cellular pathways. These cell lines allow for the investigation of the role and relevance of TOX2 in different biological processes, providing researchers essential tools for functional assays and mechanistic studies.
The key function of TOX2 Gene Knockout Cell Lines is to facilitate the understanding of gene function and regulation through targeted gene editing techniques. Utilizing CRISPR/Cas9 technology, these cell lines exhibit a complete loss of TOX2 expression, enabling the assessment of downstream genetic pathways, cellular behaviors, and signaling cascades that rely on this gene. Such insights are crucial for elucidating the gene's contributions to diseases, particularly in immunology and cancer biology.
The scientific importance of these cell lines extends into both research and clinical settings. In the laboratory, they are invaluable for dissecting the complexities of cellular behaviors and disease mechanisms, while clinical applications may include understanding disease susceptibility and developing targeted therapies. Additionally, they serve as a critical resource for drug discovery programs, aiding in the identification of potential treatment options for conditions linked to TOX2 dysregulation.
Compared to alternative models, these knockout cell lines offer distinct advantages, including specificity, reproducibility, and the ability to model native cellular environments accurately. Unlike traditional methods that may provide only correlative data, the TOX2 Gene Knockout Cell Lines allow for precise manipulation of the gene, resulting in a clearer understanding of its role in health and disease.
For researchers and clinicians alike, the value of these cell lines lies in their capacity to accelerate research timelines, enhance experimental validity, and contribute to advancements in therapeutics. Investing in TOX2 Gene Knockout Cell Lines ensures access to cutting-edge tools that can drive innovative research and potentially transform clinical practices.
Our company is committed to advancing scientific discovery through high-quality, expertly engineered biological products, making us a reliable partner in your research endeavors. We blend scientific excellence with customer-focused solutions to deliver products that meet the evolving needs of the scientific community.
Please note that all services are for research use only. Not intended for any clinical use.
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