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TMEM218 Knockout Cell Lines

Gene: TMEM218

Official Full Name: transmembrane protein 218provided by HGNC

Gene Summary: Predicted to be located in cilium and membrane. Implicated in Joubert syndrome. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO28379 TMEM218 Knockout cell line (HeLa) Human TMEM218 1:3~1:6 Negative Online Inquiry
KO28380 TMEM218 Knockout cell line (HCT 116) Human TMEM218 1:2~1:4 Negative Online Inquiry
KO28381 TMEM218 Knockout cell line (HEK293) Human TMEM218 1:3~1:6 Negative Online Inquiry
KO28382 TMEM218 Knockout cell line (A549) Human TMEM218 1:3~1:4 Negative Online Inquiry

Background

TMEM218 Gene Knockout Cell Lines are genetically engineered cellular models specifically designed to facilitate the study of the TMEM218 gene's role in various biological processes. This product employs advanced CRISPR/Cas9 technology to create precise knockouts of the TMEM218 gene, allowing researchers to investigate the gene's functions through controlled experimental conditions. The perturbation of this gene provides insights into cellular behaviors, signaling pathways, and interactions that may be pivotal in understanding various diseases, including cancer.

The key mechanism underpinning this product lies in its ability to enable the study of gene function by abolishing TMEM218 expression. This knockout model can help elucidate the gene's contribution to cellular differentiation, proliferation, and response to external stimuli, thus bridging gaps in our knowledge linked to gene regulation and disease pathology.

In scientific research and clinical applications, these cell lines are particularly valuable as they can be utilized to unravel the mechanistic basis of diseases, explore therapeutic targets, and validate drug responses. Moreover, they offer a platform for high-throughput screening of drug candidates, ultimately aiding in the development of targeted therapies.

TMEM218 Gene Knockout Cell Lines stand out due to their specificity and reliability compared to other methods that attempt to silence gene expression, such as RNA interference, which can yield off-target effects. This leads to greater confidence in experimental results. Furthermore, the ease of use, reproducibility, and compatibility with various assay systems make these cell lines indispensable tools for both foundational and translational research.

For researchers and clinicians seeking to deepen their understanding of TMEM218 and its implications in health and disease, the value of these knockout cell lines is undeniable. Our company boasts extensive expertise in gene editing technologies and a commitment to delivering high-quality biological products tailored to meet the needs of the scientific community. By choosing our TMEM218 Gene Knockout Cell Lines, users gain access to a robust platform that enhances their research capabilities and accelerates discoveries in molecular biology.

Please note that all services are for research use only. Not intended for any clinical use.

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