Home / TMEM139 Knockout Cell Lines

TMEM139 Knockout Cell Lines

Gene: TMEM139

Official Full Name: transmembrane protein 139provided by HGNC

Gene Summary: Predicted to be located in membrane. [provided by Alliance of Genome Resources, Apr 2025]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO26379 TMEM139 Knockout cell line (HeLa) Human TMEM139 1:3~1:6 Negative Online Inquiry
KO26380 TMEM139 Knockout cell line (HCT 116) Human TMEM139 1:2~1:4 Negative Online Inquiry
KO26381 TMEM139 Knockout cell line (A549) Human TMEM139 1:3~1:4 Negative Online Inquiry

Background

TMEM139 Gene Knockout Cell Lines are engineered cellular models specifically designed to study the role of the TMEM139 gene in various biological processes. This product encompasses a suite of cell lines generated through CRISPR/Cas9 technology, ensuring precise gene editing that results in a complete ablation of TMEM139 expression. The elimination of this gene provides researchers with valuable insight into its function, underlying pathways, and its potential implications in disease states.

The primary mechanism of action involves the targeted disruption of the TMEM139 gene, leading to a lack of gene expression and resulting alterations in cellular behavior, signaling, and phenotypic characteristics. This allows for the study of both gain-of-function and loss-of-function effects in biological pathways where TMEM139 is believed to be implicated. Through these knockout models, scientists can delve into the contributions of TMEM139 to processes such as cellular differentiation, immune response, and neoplastic transformation, thus illuminating its potential roles in therapeutic applications.

The scientific importance of TMEM139 Gene Knockout Cell Lines cannot be overstated, as they are pivotal for advancing research in fields like cancer biology, neurobiology, and developmental biology. Their applications in drug discovery, biomarker identification, and understanding gene-environment interactions position them as indispensable tools within both academic and clinical research settings.

Compared to conventional methods, such as RNA interference, these knockout cell lines offer enhanced specificity and efficiency in gene ablation. They retain a stable genetic background and mimic in vivo conditions more accurately, yielding reproducible results that bolster the reliability of experimental outcomes. This reliability is further supported by the robust validation of gene knockout efficacy through genotyping and functional assays.

For researchers and clinicians alike, the TMEM139 Gene Knockout Cell Lines offer an unparalleled resource for deciphering the complexities of gene function and its implications in health and disease. By selecting this product, users position themselves at the forefront of cutting-edge research, equipped with tools that foster discovery and innovation.

Our company specializes in providing high-quality, customizable biological products that cater to the evolving needs of the scientific community. With a commitment to rigorous quality control and outstanding customer support, we ensure our products meet the exacting standards of researchers and clinicians worldwide.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.