Gene: TIMD4
Official Full Name: T cell immunoglobulin and mucin domain containing 4provided by HGNC
Gene Summary: Predicted to enable phosphatidylserine binding activity. Predicted to be involved in apoptotic cell clearance and cytoskeletal rearrangement involved in phagocytosis, engulfment. Predicted to be located in extracellular region and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO03838 | TIMD4 Knockout cell line (A549) | Human | TIMD4 | 1:3~1:4 | Negative | Online Inquiry |
TIMD4 Gene Knockout Cell Lines are engineered cellular models designed to investigate the specific functions of the TIMD4 gene, which encodes a protein known to modulate immune responses through its interactions with phosphatidylserine. By utilizing CRISPR/Cas9 gene-editing technology, these cell lines facilitate targeted knockout of the TIMD4 gene, allowing researchers to elucidate its biological roles and optimize experiments focused on cell signaling, immunology, and disease pathophysiology.
These cell lines operate through the selective disruption of TIMD4 expression, leading to the downregulation of pathways involved in immune regulation and potentially revealing unique mechanisms of cell death and clearance during immune responses. The depletion of TIMD4 provides a platform for studying the effects of its absence on cell proliferation, differentiation, and apoptosis, thereby expanding our understanding of T cell regulation and autoimmunity.
The scientific importance of TIMD4 Gene Knockout Cell Lines is underscored by their utility in both basic and translational research. These models enable investigators to explore the role of TIMD4 in various conditions, such as cancer, autoimmune disorders, and infectious diseases, making them invaluable for developing novel therapeutic approaches.
What sets these cell lines apart from existing alternatives is their precise editing capability, which leads to consistent and reproducible experimental outcomes. Unlike traditional gene silencing methods such as RNA interference, the genetic knockout provides a stable mutation, eliminating off-target effects and diminishing variability in experimental results.
For researchers and clinicians, the value of TIMD4 Gene Knockout Cell Lines cannot be overstated. They offer a robust tool for dissecting complex immunological pathways, facilitating advancements in targeted therapies and biomarker discovery. As a company with extensive expertise in bioscience research products, we are committed to providing high-quality cellular models that meet the rigorous demands of the scientific community. Our TIMD4 Gene Knockout Cell Lines are meticulously designed to support your research initiatives and contribute to breakthroughs in immunology and beyond.
Please note that all services are for research use only. Not intended for any clinical use.
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