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TEAD2 Knockout Cell Lines

Gene: TEAD2

Official Full Name: TEA domain transcription factor 2provided by HGNC

Gene Summary: Enables several functions, including DNA-binding transcription factor activity; disordered domain specific binding activity; and transcription coactivator binding activity. Involved in hippo signaling; positive regulation of DNA-templated transcription; and protein-containing complex assembly. Located in cytosol and nucleoplasm. Part of TEAD-YAP complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO08508 TEAD2 Knockout cell line (HeLa) Human TEAD2 1:3~1:6 Negative Online Inquiry
KO08509 TEAD2 Knockout cell line (HCT 116) Human TEAD2 1:2~1:4 Negative Online Inquiry
KO08510 TEAD2 Knockout cell line (HEK293) Human TEAD2 1:3~1:6 Negative Online Inquiry
KO08511 TEAD2 Knockout cell line (A549) Human TEAD2 1:3~1:4 Negative Online Inquiry

Background

TEAD2 Gene Knockout Cell Lines are meticulously engineered cellular models in which the TEAD2 gene, a transcription factor integral to various signaling pathways, has been selectively disrupted. This gene plays a pivotal role in mediating cellular responses to the Hippo signaling pathway and is essential for regulating cell proliferation and differentiation. By creating knockout cell lines, researchers can effectively study the direct effects of TEAD2 depletion on cellular functions, revealing insights into gene expression, tumorigenesis, and other critical biological processes.

The primary function of these knockout cell lines lies in their ability to facilitate the investigation of TEAD2-associated pathways, particularly their implications in cancer biology and regenerative medicine. Without the influence of TEAD2, researchers can assess the alterations in signaling cascades that govern cellular behavior, thus enhancing our understanding of oncogenic potential and cellular plasticity. This unique mechanism also allows for the exploration of new therapeutic targets and the development of novel intervention strategies.

The scientific significance of TEAD2 Gene Knockout Cell Lines extends to various research and clinical applications, including drug screening, gene therapy, and the development of personalized medicine approaches. By providing a reliable platform to study TEAD2 function, these cell lines serve as invaluable tools for elucidating the molecular underpinnings of disease and the effects of pharmacological agents.

What sets TEAD2 Gene Knockout Cell Lines apart from alternative products is their specificity and quality. These cell lines are generated using advanced genome-editing techniques, ensuring precise knockout of the gene with minimal off-target effects. This high level of specificity enhances experimental reproducibility and reliability, thereby maximizing the value of research outcomes.

In summary, TEAD2 Gene Knockout Cell Lines represent a critical resource for researchers and clinicians seeking to deepen their understanding of TEAD2's role in cellular processes and disease mechanisms. With a commitment to scientific excellence and innovation, our company offers these high-quality cell lines to empower the scientific community in advancing cell biology and translational research.

Please note that all services are for research use only. Not intended for any clinical use.

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