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STX3 Knockout Cell Lines

Gene: STX3

Official Full Name: syntaxin 3provided by HGNC

Gene Summary: The gene is a member of the syntaxin family. The encoded protein is targeted to the apical membrane of epithelial cells where it forms clusters and is important in establishing and maintaining polarity necessary for protein trafficking involving vesicle fusion and exocytosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO35189 STX3 Knockout cell line (HeLa) Human STX3 1:3~1:6 Negative Online Inquiry
KO35190 STX3 Knockout cell line (HCT 116) Human STX3 1:2~1:4 Negative Online Inquiry
KO35191 STX3 Knockout cell line (HEK293) Human STX3 1:3~1:6 Negative Online Inquiry
KO35192 STX3 Knockout cell line (A549) Human STX3 1:3~1:4 Negative Online Inquiry

Background

STX3 Gene Knockout Cell Lines represent a cutting-edge biological tool designed to facilitate the study of the syntaxin family of proteins, particularly STX3, which plays a critical role in various cellular processes including exocytosis and intracellular transport. Through targeted knockout techniques, these cell lines allow researchers to efficiently investigate the functional implications of STX3 deficiency in a controlled environment, thereby elucidating its contributions to cellular homeostasis and intercellular communication.

The primary function of STX3 Gene Knockout Cell Lines lies in their ability to silence the STX3 gene, enabling the assessment of phenotypic alterations resulting from the absence of this essential protein. Mechanistically, the knockout impedes the formation of SNARE complexes that are crucial for vesicle fusion, presenting a pathway to observe downstream effects on neurotransmitter release and secretion of soluble factors that influence various physiological processes. This functional insight is invaluable in dissecting the mechanistic roles of STX3 in health and disease.

In the scientific landscape, the STX3 Gene Knockout Cell Lines hold significant importance in both research and clinical applications. They are particularly advantageous for investigating neurodegenerative disorders, metabolic syndromes, and cancer biology, where STX3's regulatory influence on cell signaling and membrane dynamics is critical. These cell lines offer a reliable platform for drug screening and the evaluation of potential therapeutic interventions, thereby accelerating the path from bench to bedside.

What sets our STX3 Gene Knockout Cell Lines apart from other genetic models is not just the precision of the knockout approach but also the robustness and reproducibility of results observed across experiments. This reliability is further enhanced by our rigorous quality control protocols and extensive characterization studies, ensuring that researchers receive a product that meets the highest scientific standards.

For researchers and clinicians dedicated to advancing their understanding of gene function and its implications in disease, our STX3 Gene Knockout Cell Lines embody an essential resource that can significantly enhance experimental outcomes. With our company's deep expertise in genetic engineering and commitment to providing high-quality biological products, you can trust that you are equipping your lab with tools that will drive innovation and discovery in your research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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