Home / STARD3 Knockout Cell Lines

STARD3 Knockout Cell Lines

Gene: STARD3

Official Full Name: StAR related lipid transfer domain containing 3provided by HGNC

Gene Summary: This gene encodes a member of a subfamily of lipid trafficking proteins that are characterized by a C-terminal steroidogenic acute regulatory domain and an N-terminal metastatic lymph node 64 domain. The encoded protein localizes to the membranes of late endosomes and may be involved in exporting cholesterol. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO03199 STARD3 Knockout cell line (HeLa) Human STARD3 1:3~1:6 Negative Online Inquiry
KO03200 STARD3 Knockout cell line (HCT 116) Human STARD3 1:2~1:4 Negative Online Inquiry
KO03201 STARD3 Knockout cell line (HEK293) Human STARD3 1:3~1:6 Negative Online Inquiry
KO03202 STARD3 Knockout cell line (A549) Human STARD3 1:3~1:4 Negative Online Inquiry

Background

STARD3 Gene Knockout Cell Lines are specialized cellular models in which the STARD3 gene, known for its role in intracellular cholesterol transport, has been inactivated or "knocked out." This innovative tool allows researchers to study the physiological and pathological implications of STARD3 deficiency, particularly in the context of lipid metabolism, cellular signaling, and disease processes such as cancer, neurodegeneration, and cardiovascular disorders.

The primary mechanism of action for the STARD3 knockout involves the absence of STARD3 protein, which disrupts the transport of cholesterol from the endosomal compartment to the plasma membrane and other organelles. Consequently, this model permits an in-depth exploration of how altered lipid homeostasis affects cell function, signaling pathways, and the overall cellular response to stress.

Scientifically, the STARD3 Gene Knockout Cell Lines are indispensable for research and potential therapeutic applications, offering insights into the molecular underpinnings of diseases linked to cholesterol dysregulation. In clinical settings, these models hold promise for drug discovery and the development of novel interventions targeting lipid metabolism-related conditions.

What sets our STARD3 Gene Knockout Cell Lines apart from competitor products is our rigorous validation process, ensuring that the knockout is complete and functionally relevant. Furthermore, we provide comprehensive user support, including detailed protocols and troubleshooting assistance, making it easier for researchers to integrate these cell lines into their studies.

By investing in our STARD3 Gene Knockout Cell Lines, researchers and clinicians gain access to a powerful tool for understanding the complexities of lipid transport and its implications for human health. Our commitment to excellence in biological product development and deep expertise in gene editing technologies positions us as a trusted partner in advancing scientific knowledge and clinical applications.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.