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SRM Knockout Cell Lines

Gene: SRM

Official Full Name: spermidine synthaseprovided by HGNC

Gene Summary: The polyamines putrescine, spermine, and spermidine are ubiquitous polycationic mediators of cell growth and differentiation. Spermidine synthase is one of four enzymes in the polyamine-biosynthetic pathway and carries out the final step of spermidine biosynthesis. This enzyme catalyzes the conversion of putrescine to spermidine using decarboxylated S-adenosylmethionine as the cofactor. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO35223 SRM Knockout cell line (HeLa) Human SRM 1:3~1:6 Negative Online Inquiry
KO35224 SRM Knockout cell line (HCT 116) Human SRM 1:2~1:4 Negative Online Inquiry
KO35225 SRM Knockout cell line (HEK293) Human SRM 1:3~1:6 Negative Online Inquiry
KO35226 SRM Knockout cell line (A549) Human SRM 1:3~1:4 Negative Online Inquiry

Background

SRM Gene Knockout Cell Lines are genetically engineered cell lines that have had specific genes systematically disrupted or eliminated, allowing researchers to study the resulting phenotypic and molecular changes. By creating precise gene knockouts, these cell lines serve as invaluable tools for understanding gene function, regulation, and the biological pathways in which they participate. The knockout mechanism primarily utilizes CRISPR-Cas9 technology, which provides high efficiency and specificity in generating targeted mutations, ensuring the resultant cell lines are relevant for experimental needs.

These cell lines play a critical role in a wide array of scientific applications, including functional genomics, drug discovery, and toxicity testing. In clinical research, they are integral for elucidating gene-disease relationships, which can aid in developing targeted therapies and advanced diagnostic approaches. Furthermore, SRM Gene Knockout Cell Lines can be utilized in various model organisms and systems to further validate genetic hypotheses, offering insights that are directly translatable to human health.

One of the key advantages of SRM Gene Knockout Cell Lines is their rigorous validation steps, ensuring high-quality, consistent results across experiments. Unlike traditional knockout methodologies, which can yield off-target effects or low efficiency, our cell lines are created using cutting-edge precision techniques. This robustness reduces variability, greatly enhancing reproducibility in research findings.

For researchers and clinicians, the ability to dissect complex biological processes and validate therapeutic targets simplifies the pathway from laboratory investigation to clinical application, making SRM Gene Knockout Cell Lines an essential resource in modern biomedical research. At our company, we pride ourselves on leveraging cutting-edge genetic engineering technologies and adhering to best practices to deliver high-quality biological products tailored to meet the evolving needs of the scientific community.

Please note that all services are for research use only. Not intended for any clinical use.

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