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SP4 Knockout Cell Lines

Gene: SP4

Official Full Name: Sp4 transcription factorprovided by HGNC

Gene Summary: The protein encoded by this gene is a transcription factor that can bind to the GC promoter region of a variety of genes, including those of the photoreceptor signal transduction system. The encoded protein binds to the same sites in promoter CpG islands as does the transcription factor SP1, although its expression is much more restricted compared to that of SP1. This gene may be involved in bipolar disorder and schizophrenia. [provided by RefSeq, May 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO35296 SP4 Knockout cell line (HeLa) Human SP4 1:3~1:6 Negative Online Inquiry
KO35297 SP4 Knockout cell line (HCT 116) Human SP4 1:2~1:4 Negative Online Inquiry
KO35298 SP4 Knockout cell line (HEK293) Human SP4 1:3~1:6 Negative Online Inquiry
KO35299 SP4 Knockout cell line (A549) Human SP4 1:3~1:4 Negative Online Inquiry

Background

SP4 Gene Knockout Cell Lines are specialized cellular models engineered to facilitate the study of gene function and regulation through the targeted disruption of the SP4 transcription factor gene. These cell lines serve as a pivotal tool for researchers investigating the downstream effects of SP4 modulation on cellular behavior, providing insights into gene expression pathways and related biological processes.

The SP4 gene plays a critical role in numerous physiological functions, including but not limited to neural development, cardiovascular health, and cancer progression. By employing CRISPR/Cas9 technology, our SP4 Gene Knockout Cell Lines demonstrate a high efficiency in gene editing, effectively creating a loss-of-function model. This allows investigators to observe phenotypic changes in response to the absence of SP4, analyzing the resultant alterations at molecular, cellular, and organismal levels.

Scientifically, these cell lines are invaluable not only for basic research but also for translational applications, particularly in drug discovery and disease modeling. By elucidating the roles of SP4 in health and disease, researchers can identify novel therapeutic targets and evaluate the efficacy of potential interventions.

What sets our SP4 Gene Knockout Cell Lines apart from alternative cellular models is the rigorous quality control measures in place during the development process, ensuring consistent performance and replicability in experimental contexts. Furthermore, these cell lines are compatible with various assays, including high-throughput screening, making them a versatile addition to any laboratory.

For researchers and clinicians eager to unlock the complexities of gene regulation and its implications in biological research and therapy, SP4 Gene Knockout Cell Lines represent a powerful asset. Our commitment to excellence in bioproduct development is backed by a team of experts dedicated to supporting the scientific community with innovative and reliable solutions.

Please note that all services are for research use only. Not intended for any clinical use.

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