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SLC26A7 Knockout Cell Lines

Gene: SLC26A7

Official Full Name: solute carrier family 26 member 7provided by HGNC

Gene Summary: This gene is one member of a family of sulfate/anion transporter genes. Family members are well conserved in gene structure and protein length yet have markedly different tissue expression patterns. This gene has abundant and specific expression in the kidney. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Aug 2013]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30649 SLC26A7 Knockout cell line (HCT 116) Human SLC26A7 1:2~1:4 Negative Online Inquiry

Background

SLC26A7 Gene Knockout Cell Lines are genetically engineered cell lines where the SLC26A7 gene has been disrupted or "knocked out." The SLC26A7 gene encodes a member of the solute carrier family involved in the transport of anions and plays a pivotal role in epithelial ion transport and pH regulation. By utilizing CRISPR-Cas9 technology, these cell lines provide researchers with a powerful tool for studying the physiological roles of SLC26A7 in various cellular processes, including bicarbonate transport and intercellular communication.

The knockout mechanism effectively removes SLC26A7 function, allowing scientists to observe the resulting phenotypic changes in ion transport and homeostasis. This process can elucidate the gene's contribution to diseases such as cystic fibrosis, where altered ion transport is implicated. In both laboratory research and clinical settings, these cell lines serve as a crucial model for understanding the pathophysiology of related conditions and developing potential therapeutics.

One of the primary advantages of SLC26A7 Gene Knockout Cell Lines is their specificity; unlike general ion transport inhibitors, these cells allow for targeted functional studies of the SLC26A7 gene. This specificity facilitates cleaner data and aids in dissecting the gene's unique roles compared to other solute carriers. Furthermore, they are versatile and can be utilized in a range of assays, including electrophysiology and drug testing, making them indispensable for any research focused on ion transport.

Researchers and clinicians will find immense value in SLC26A7 Gene Knockout Cell Lines as they seek to accelerate advancements in understanding ion homeostasis implications in health and disease. By providing a tailored model for in-depth exploration of the SLC26A7 gene, our product stands out as an essential addition to any laboratory's toolkit.

Our company is dedicated to advancing research through high-quality biological products supported by extensive expertise in molecular biology. We strive to empower scientists with the tools they need to lead the way in innovative research and clinical developments.

Please note that all services are for research use only. Not intended for any clinical use.

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