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SERINC2 Knockout Cell Lines

Gene: SERINC2

Official Full Name: serine incorporator 2provided by HGNC

Gene Summary: Predicted to enable acetyltransferase activator activity. Predicted to be involved in phosphatidylserine metabolic process. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14201 SERINC2 Knockout cell line (HeLa) Human SERINC2 1:3~1:6 Negative Online Inquiry
KO14202 SERINC2 Knockout cell line (HCT 116) Human SERINC2 1:2~1:4 Negative Online Inquiry
KO14203 SERINC2 Knockout cell line (HEK293) Human SERINC2 1:3~1:6 Negative Online Inquiry
KO14204 SERINC2 Knockout cell line (A549) Human SERINC2 1:3~1:4 Negative Online Inquiry

Background

SERINC2 Gene Knockout Cell Lines are specialized cellular models created through targeted gene editing to disrupt the SERINC2 gene, which is implicated in various aspects of cell function and viral interactions. These knockout cell lines serve as invaluable tools for studying the biological roles of SERINC2 in processes such as immune response modulation and the enhancement of viral entry or replication by retroviruses. By excising the SERINC2 gene, researchers can observe the alterations in cellular behavior, thereby elucidating the gene's contributions to viral pathogenesis and potential therapeutic strategies.

The key function of these cell lines lies in their ability to mimic the loss-of-function scenario of the SERINC2 gene. Researchers can utilize these cells to perform a range of experiments, including viral infection assays, biochemical analyses, and phenotypic characterization. The mechanistic insights gained from using SERINC2 knockout models have significant implications for understanding how certain viruses exploit host cell machinery and circumvent innate immune responses.

In both research and clinical settings, SERINC2 Gene Knockout Cell Lines are particularly important for studies related to virology, immunology, and therapeutic development. They provide a robust platform for drug discovery and testing, especially in evaluating novel antiviral compounds. The specificity of SERINC2 knockout enhances the reliability of results, making it easier to dissect the gene's role in viral entry and replication cycles.

Compared to traditional cell lines, the SERINC2 knockout variants offer unique advantages, such as greater accuracy in modeling human diseases associated with SERINC2 dysregulation, alongside rigorous controls that facilitate high-confidence experimental outcomes. By filling a critical gap in the existing biological models, these cell lines allow for faster and more efficient data generation.

For researchers and clinicians, the SERINC2 Gene Knockout Cell Lines represent a valuable asset that supports cutting-edge studies aimed at understanding and manipulating viral behavior. The potential for application in therapy development and enhancing our understanding of viral diseases makes this product indispensable. Our company specializes in providing high-quality genomic tools that empower the scientific community, ensuring that researchers have access to innovative solutions that drive discovery and advancement in the field of molecular biology and virology.

Please note that all services are for research use only. Not intended for any clinical use.

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