Home / SEC14L1 Knockout Cell Lines

SEC14L1 Knockout Cell Lines

Gene: SEC14L1

Official Full Name: SEC14 like lipid binding 1provided by HGNC

Gene Summary: The protein encoded by this gene belongs to the SEC14 cytosolic factor family. It has similarity to yeast SEC14 and to Japanese flying squid RALBP which suggests a possible role of the gene product in an intracellular transport system. Multiple alternatively spliced transcript variants have been found for this gene; some variants represent read-through transcripts that include exons from the upstream gene C17orf86. [provided by RefSeq, Feb 2011]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO05125 SEC14L1 Knockout cell line (HeLa) Human SEC14L1 1:3~1:6 Negative Online Inquiry
KO05126 SEC14L1 Knockout cell line (HCT 116) Human SEC14L1 1:2~1:4 Negative Online Inquiry
KO05127 SEC14L1 Knockout cell line (HEK293) Human SEC14L1 1:3~1:6 Negative Online Inquiry
KO05128 SEC14L1 Knockout cell line (A549) Human SEC14L1 1:3~1:4 Negative Online Inquiry

Background

SEC14L1 Gene Knockout Cell Lines are specially engineered cell lines that have undergone targeted genetic modifications to completely inactivate the SEC14L1 gene. This gene encodes for a protein involved in lipid homeostasis and has been implicated in various cellular processes, including membrane trafficking and secretion. By providing researchers with a model that lacks SEC14L1 expression, these knockout cell lines facilitate investigations into the gene's role within cellular functions and its potential involvement in disease mechanisms, especially in conditions related to lipid metabolism and neurodegenerative disorders.

The primary function of the SEC14L1 knockout is to allow researchers to elucidate the biological pathways that may be disrupted in the absence of this gene. This knockout model offers insights into lipid binding properties, signaling pathways, and cellular stress responses. By utilizing these specific cell lines, scientists can conduct loss-of-function studies that help clarify the gene's contribution to cellular behavior and disease pathophysiology, thereby enhancing our understanding of lipid-related disorders.

Scientifically, SEC14L1 Gene Knockout Cell Lines hold significant value in research and clinical settings. They serve as crucial tools for screening potential therapeutic compounds, assessing drug efficacy, and observing disease progression in various models. Their application spans fundamental biology, pharmacology, and translational research, making them an invaluable asset for laboratories aiming to advance drug discovery or therapeutic strategies for conditions linked to lipid dysregulation.

Compared to alternative genetic models, SEC14L1 knockout cell lines offer distinct advantages, including higher specificity, reproducibility, and the ability to study gene function without confounding factors introduced by partial gene activity. Moreover, they are ready-to-use and fully validated for experimental use, which streamlines research workflows and accelerates discovery timelines.

In summary, SEC14L1 Gene Knockout Cell Lines are a must-have for researchers and clinicians focused on lipid metabolism and related diseases. These innovative tools, backed by our commitment to scientific excellence and the highest standards in product quality, empower users with the resources necessary for groundbreaking research that can ultimately impact patient care and therapeutic development.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.