Home / RUFY2 Knockout Cell Lines

RUFY2 Knockout Cell Lines

Gene: RUFY2

Official Full Name: RUN and FYVE domain containing 2provided by HGNC

Gene Summary: Enables SH3 domain binding activity. Predicted to be involved in regulation of endocytosis. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14390 RUFY2 Knockout cell line (HeLa) Human RUFY2 1:3~1:6 Negative Online Inquiry
KO14391 RUFY2 Knockout cell line (HCT 116) Human RUFY2 1:2~1:4 Negative Online Inquiry
KO14392 RUFY2 Knockout cell line (HEK293) Human RUFY2 1:3~1:6 Negative Online Inquiry
KO14393 RUFY2 Knockout cell line (A549) Human RUFY2 1:3~1:4 Negative Online Inquiry

Background

RUFY2 Gene Knockout Cell Lines are genetically modified cell lines designed to eliminate the expression of the RUFY2 gene, which plays a critical role in cellular signaling and various biological processes. By employing CRISPR-Cas9 technology, these cell lines enable researchers to study the functional consequences of RUFY2 gene depletion and its implications in cellular behavior, particularly in areas such as cancer biology, neurodegeneration, and immune responses.

The key mechanism at work involves the precise editing of the genomic DNA, leading to frameshift mutations or deletions that result in a complete knockout of the RUFY2 protein. This gene's absence allows for the assessment of downstream effects on signaling pathways, cellular proliferation, and apoptosis, providing essential insights into RUFY2-mediated physiological processes.

Scientifically, RUFY2 Gene Knockout Cell Lines hold substantial importance for researchers interested in elucidating the gene's role in disease mechanisms. The ability to create specific knockout models accelerates the investigation of target validation for therapeutic approaches and drug development in both academic and clinical settings. Furthermore, utilizing these cell lines can lead to novel biomarker discoveries and improved understanding of disease pathogenesis.

One of the primary advantages of our RUFY2 Gene Knockout Cell Lines is their high specificity and efficiency in gene editing, allowing for a much more controlled experimental environment compared to traditional methods such as RNA interference. This specificity reduces off-target effects and increases the reliability of experimental outcomes, making it an indispensable tool for researchers and clinicians attempting to dissect complex biological pathways.

For researchers, clinicians, and biopharmaceutical companies, investing in RUFY2 Gene Knockout Cell Lines not only provides a unique avenue for in-depth research but also propels advancements in understanding critical disease processes that could lead to innovative therapeutic strategies. Our company has extensive expertise in developing high-quality biological products tailored for research needs, ensuring that each product is rigorously tested and validated for utmost reliability and performance in laboratory settings.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.