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RNF214 Knockout Cell Lines

Gene: RNF214

Official Full Name: ring finger protein 214provided by HGNC

Gene Summary: Predicted to enable ubiquitin-protein transferase activity. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO02798 RNF214 Knockout cell line (HeLa) Human RNF214 1:3~1:6 Negative Online Inquiry
KO02799 RNF214 Knockout cell line (HCT 116) Human RNF214 1:2~1:4 Negative Online Inquiry
KO02800 RNF214 Knockout cell line (HEK293) Human RNF214 1:3~1:6 Negative Online Inquiry
KO02801 RNF214 Knockout cell line (A549) Human RNF214 1:3~1:4 Negative Online Inquiry

Background

RNF214 Gene Knockout Cell Lines are engineered cellular models characterized by the deliberate deletion of the RNF214 gene, which encodes a protein implicated in various cellular processes such as cell proliferation, differentiation, and DNA repair mechanisms. The cell lines are generated through advanced gene-editing technologies, specifically CRISPR/Cas9, allowing precise modifications that facilitate the comprehensive study of RNF214's biological role.

The key functions of RNF214 gene knockout cell lines revolve around elucidating pathways involving ubiquitination and protein homeostasis. By abolishing RNF214 expression, researchers can investigate its influence on the cellular response to stress, apoptosis, and the regulation of oncoproteins in tumorigenesis, hence enabling a better understanding of its contribution to conditions like cancer and other genetic disorders. These cell lines serve as invaluable tools in drug development and translational research, offering insights that could lead to targeted therapies.

The scientific importance of RNF214 gene knockout cell lines lies in their ability to provide a controlled environment for examining the consequences of gene loss, insights that other models may fail to deliver. Compared to traditional cell models or non-targeted approaches, these knockout lines offer superior specificity and reproducibility, empowering researchers to dissect complex biological interactions with a greater degree of accuracy.

Key advantages of our RNF214 Gene Knockout Cell Lines include optimized growth conditions, validated performance metrics, and comprehensive technical support, all designed to enhance experimental outcomes. These lines allow researchers and clinicians not only to investigate the fundamental biology of RNF214 but also to contribute to the broader understanding of its implications in human health.

Investing in RNF214 Gene Knockout Cell Lines equips researchers with a cutting-edge resource that can drive innovative discoveries and research breakthroughs. Our company is committed to delivering high-quality biological products backed by extensive expertise in gene editing and cell line development, ensuring that our customers can confidently advance their research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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