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RASA4B Knockout Cell Lines

Gene: RASA4B

Official Full Name: RAS p21 protein activator 4Bprovided by HGNC

Gene Summary: Predicted to enable GTPase activator activity; metal ion binding activity; and phospholipid binding activity. Predicted to be involved in cellular response to calcium ion; intracellular signal transduction; and negative regulation of Ras protein signal transduction. Predicted to be located in cytosol and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO08981 RASA4B Knockout cell line (HeLa) Human RASA4B 1:3~1:6 Negative Online Inquiry
KO08982 RASA4B Knockout cell line (HCT 116) Human RASA4B 1:2~1:4 Negative Online Inquiry
KO08983 RASA4B Knockout cell line (HEK293) Human RASA4B 1:3~1:6 Negative Online Inquiry
KO08984 RASA4B Knockout cell line (A549) Human RASA4B 1:3~1:4 Negative Online Inquiry

Background

RASA4B Gene Knockout Cell Lines are specially engineered cellular models that facilitate the study of the RASA4B gene's role in various biological processes. By employing CRISPR-Cas9 technology, these knockout cell lines feature a targeted inactivation of the RASA4B gene, enabling researchers to investigate the downstream effects of its absence on cellular signaling pathways and functions.

The primary mechanism of action involves the disruption of gene expression, leading to the loss of RASA4B protein function, which plays a crucial role in regulating cell proliferation, differentiation, and apoptosis through its involvement in Ras signaling. Consequently, these knockout models serve as valuable tools for elucidating the gene’s involvement in cancer biology, developmental processes, and other pathological conditions linked to aberrant signaling.

In scientific and clinical research, RASA4B Gene Knockout Cell Lines are essential for understanding the specific pathways influenced by this gene. Their applications extend to drug discovery, where researchers can evaluate potential therapeutics targeting Ras-modulated pathways, as well as the development of precision medicine strategies in oncology.

What sets these knockout cell lines apart is their high specificity and reproducibility, enabling more reliable results compared to other gene inactivation methods. Additionally, our commitment to rigorous quality control ensures that these cell lines remain genetically stable, thereby enhancing the validity of experimental findings over time.

For researchers and clinicians aiming to gain insights into the intricate mechanisms of RASA4B, our cell lines provide a cutting-edge solution backed by our years of expertise in developing high-quality biological products. By advancing your understanding of gene function and cellular dynamics, RASA4B Gene Knockout Cell Lines represent a valuable asset in your research portfolio.

Please note that all services are for research use only. Not intended for any clinical use.

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