Gene: RABEP1
Official Full Name: rabaptin, RAB GTPase binding effector protein 1provided by HGNC
Gene Summary: Enables protein domain specific binding activity and protein homodimerization activity. Involved in vesicle-mediated transport. Located in endocytic vesicle and endosome. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO33559 | RABEP1 Knockout cell line (HeLa) | Human | RABEP1 | 1:3~1:6 | Negative | Online Inquiry |
KO33560 | RABEP1 Knockout cell line (HCT 116) | Human | RABEP1 | 1:2~1:4 | Negative | Online Inquiry |
KO33561 | RABEP1 Knockout cell line (HEK293) | Human | RABEP1 | 1:3~1:6 | Negative | Online Inquiry |
KO33562 | RABEP1 Knockout cell line (A549) | Human | RABEP1 | 1:3~1:4 | Negative | Online Inquiry |
RABEP1 Gene Knockout Cell Lines represent a pivotal tool in the field of molecular biology, specifically designed for the investigation of Rab protein function and associated cellular processes. RABEP1, a member of the Rab family of small GTPases, is known for its crucial role in endosomal trafficking and membrane fusion, making it an essential target for understanding various cellular pathways and disease mechanisms, particularly in cancer and neurological disorders.
These knockout cell lines are genetically modified to lack the RABEP1 gene, facilitating the study of cellular responses devoid of this critical protein. By disrupting RABEP1 expression, researchers can elucidate its impact on endocytosis, vesicle trafficking, and signal transduction pathways. The functionality of these cell lines is grounded in their ability to replicate physiological conditions while providing a controlled environment to assess the consequences of the gene's absence on cellular behavior.
Scientific inquiry utilizing RABEP1 knockout cell lines is of high importance, as it can potentially reveal novel therapeutic targets for drug development in oncogenesis or neurodegeneration. In clinical settings, these cell lines can serve as valuable models for screening putative pharmacological agents, allowing researchers to explore interactions and effects on disease pathophysiology with greater precision.
What sets RABEP1 Gene Knockout Cell Lines apart from alternative models is their specificity and reliability. Unlike transient knockdown approaches, which can yield variable results, these stable knockout lines provide consistent and reproducible data due to the complete loss of the target gene. This allows for a more straightforward analysis of downstream effects and enhances the validity of experimental outcomes.
For researchers, clinicians, and pharmaceutical developers, the RABEP1 Gene Knockout Cell Lines are not just tools; they represent an opportunity to push the boundaries of current scientific knowledge and therapeutic advances. Our company prides itself on expertise in developing high-quality genetic models that are instrumental in pioneering research, ensuring our products meet the rigorous standards necessary for impactful scientific advancement.
Please note that all services are for research use only. Not intended for any clinical use.
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