Gene: PTPRQ
Official Full Name: protein tyrosine phosphatase receptor type Qprovided by HGNC
Gene Summary: This locus encodes a member of the type III receptor-like protein-tyrosine phosphatase family. The encoded protein catalyzes the dephosphorylation of phosphotyrosine and phosphatidylinositol and plays roles in cellular proliferation and differentiation. Mutations at this locus have been linked to autosomal recessive deafness. [provided by RefSeq, Mar 2014]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO29052 | PTPRQ Knockout cell line (HeLa) | Human | PTPRQ | 1:3~1:6 | Negative | Online Inquiry |
PTPRQ Gene Knockout Cell Lines are specialized human cell lines that have been genetically engineered to have a complete knockout of the PTPRQ gene. This gene encodes a member of the protein tyrosine phosphatase family, which is involved in crucial cellular processes including growth, differentiation, and response to external stimuli. By abolishing the expression of PTPRQ, researchers can investigate its role in cellular signaling pathways, pathology, and potential therapeutic targets in various diseases, including certain cancers and neurodegenerative disorders.
The primary function of these knockout cell lines is to provide a reliable model for functional studies of PTPRQ deficiency. Through methods such as CRISPR-Cas9 gene editing technology, the knockout is achieved with high specificity, allowing researchers to delve into the mechanistic insights of PTPRQ and its interactions within the cellular milieu. This allows for greater understanding of how disruption of this gene affects cellular behaviors, providing a valuable tool for drug discovery and development.
In research settings, these cell lines hold significant importance as they enable scientists to explore novel pathways associated with PTPRQ loss, offering insights that could lead to breakthroughs in targeted therapies. Clinically, understanding the role of PTPRQ can enhance diagnostics and therapeutic strategies in diseases characterized by dysfunction in cell signaling.
Compared to other available models, PTPRQ Gene Knockout Cell Lines offer a precise and reproducible system that stands out for its genetic fidelity and ability to recapitulate the specific pathophysiological conditions associated with PTPRQ deficiency. These knockout lines are backed by robust validation processes, ensuring that researchers can trust the data generated from their experiments.
Our company specializes in delivering innovative genetic tools to the research community. With a commitment to advancing scientific understanding through cutting-edge technology, we provide high-quality cell lines that empower researchers and clinicians to uncover new discoveries and develop effective treatments. By integrating Scientific expertise and commercial efficiency, we aim to support the advancement of biological research and its application in the clinical setting.
Please note that all services are for research use only. Not intended for any clinical use.
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