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PRIMA1 Knockout Cell Lines

Gene: PRIMA1

Official Full Name: proline rich membrane anchor 1provided by HGNC

Gene Summary: The product of this gene functions to organize acetylcholinesterase (AChE) into tetramers, and to anchor AChE at neural cell membranes. [provided by RefSeq, Nov 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24075 PRIMA1 Knockout cell line (HCT 116) Human PRIMA1 1:2~1:4 Negative Online Inquiry

Background

PRIMA1 Gene Knockout Cell Lines are specifically engineered cellular models designed to elucidate the functional roles of the PRIMA1 gene within various biological pathways. These knockout cell lines have been meticulously developed using advanced CRISPR/Cas9 gene-editing technology, ensuring a precise disruption of the PRIMA1 gene, allowing researchers to study its effects on cellular processes such as proliferation, differentiation, and apoptosis.

The primary mechanism of action involves the targeted inactivation of the PRIMA1 gene, which plays a crucial role in cellular responses to environmental stimuli and contributes to the regulation of cell survival. By utilizing PRIMA1 knockout cell lines, researchers can effectively analyze the downstream cascades activated by the loss of PRIMA1 function, leading to deeper insights into its involvement in pathophysiological conditions, including cancer and neurodegenerative diseases.

These knockout cell lines hold significant scientific importance, providing a platform for both academic and clinical research settings. They enable investigations into gene function, assist in drug discovery, and contribute to the development of targeted therapies aimed at restoring normal cellular behavior. The ability to manipulate the PRIMA1 gene within these cell lines makes them invaluable tools for unraveling complex biological mechanisms and therapeutic strategies.

Compared to traditional models, PRIMA1 Gene Knockout Cell Lines offer several advantages, including enhanced specificity of gene disruption and reduced off-target effects, which often confound results in older genetic manipulation approaches. Their robustness and reliability position them as superior options for scientific inquiry, affording a clearer understanding of gene function in a controlled environment.

For researchers and clinicians alike, the PRIMA1 Gene Knockout Cell Lines present a unique opportunity to advance their studies significantly, driving breakthroughs in cellular biology and therapeutic interventions. With a commitment to excellence in cellular engineering, our company specializes in delivering high-quality biological products that empower scientific discovery and innovation.

Please note that all services are for research use only. Not intended for any clinical use.

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