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PPIC Knockout Cell Lines

Gene: PPIC

Official Full Name: peptidylprolyl isomerase Cprovided by HGNC

Gene Summary: The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase)) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. Similar to other PPIases, this protein can bind immunosuppressant cyclosporin A. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO35963 PPIC Knockout cell line (HeLa) Human PPIC 1:3~1:6 Negative Online Inquiry
KO35964 PPIC Knockout cell line (HCT 116) Human PPIC 1:2~1:4 Negative Online Inquiry
KO35965 PPIC Knockout cell line (HEK293) Human PPIC 1:3~1:6 Negative Online Inquiry
KO35966 PPIC Knockout cell line (A549) Human PPIC 1:3~1:4 Negative Online Inquiry

Background

PPIC Gene Knockout Cell Lines are genetically engineered cell lines designed to facilitate the study of the protein-induced gene expression and its downstream effects. Specifically, these cell lines feature targeted deletions of the PPIC gene, which encodes the peptidyl-prolyl cis-trans isomerase C (Cyclophilin C), an important protein involved in various cellular processes including protein folding, immune response modulation, and signal transduction pathways. By using CRISPR/Cas9 or other gene-editing technologies, these cell lines provide researchers the ability to create a precise knockout environment, enabling in-depth exploration of the functional role of PPIC in both physiological and pathological states.

The PPIC Gene Knockout Cell Lines are valuable in elucidating the mechanisms underlying various diseases, especially those related to immune dysregulation and cancer. These engineered models allow scientists to investigate how the absence of the PPIC gene affects cellular behavior, including cell proliferation, differentiation, and response to stressors. Consequently, they hold significant implications for pharmaceutical research and therapeutic development.

Compared to traditional knockout strategies and other genetic manipulation techniques, our PPIC Gene Knockout Cell Lines offer enhanced specificity and efficiency with minimal off-target effects, allowing for reproducible results across different experiments. They are designed with rigorous validation processes, assuring high character quality and genetic integrity—a crucial aspect for reliable experimental outcomes in both research and clinical applications.

Researchers and clinicians will find these cell lines indispensable for advancing our understanding of disease mechanisms, validating potential therapeutic targets, and screening drug candidates in a more biologically relevant context. By employing PPIC Gene Knockout Cell Lines, users can significantly accelerate their research timelines while reducing experimental variability.

Our company boasts extensive expertise in genetic engineering and has a robust portfolio of validated biological products, reflecting our commitment to facilitating groundbreaking research in molecular and cellular biology. By utilizing our products, you are partnering with a leader in scientific innovation dedicated to supporting your research needs.

Please note that all services are for research use only. Not intended for any clinical use.

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