Gene: POPDC3
Official Full Name: popeye domain cAMP effector 3provided by HGNC
Gene Summary: This gene encodes a member of the POP family of proteins containing three putative transmembrane domains. This gene is expressed in cardiac and skeletal muscle and may play an important role in these tissues during development. Alternatively spliced transcript variants have been found. [provided by RefSeq, Nov 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO20414 | POPDC3 Knockout cell line (HeLa) | Human | POPDC3 | 1:3~1:6 | Negative | Online Inquiry |
KO20415 | POPDC3 Knockout cell line (HCT 116) | Human | POPDC3 | 1:2~1:4 | Negative | Online Inquiry |
KO20416 | POPDC3 Knockout cell line (HEK293) | Human | POPDC3 | 1:3~1:6 | Negative | Online Inquiry |
KO20417 | POPDC3 Knockout cell line (A549) | Human | POPDC3 | 1:3~1:4 | Negative | Online Inquiry |
POPDC3 Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the POPDC3 gene, a member of the Popeye domain containing (POPDC) family. These cell lines serve as vital tools for elucidating the biological functions and mechanisms of the POPDC3 protein, which has been implicated in various cellular processes, including cell signaling, muscle development, and cardiac health. By creating a precise knockout of this gene, researchers can investigate the downstream effects on cellular behavior, identify pathways influenced by POPDC3, and uncover its role in disease mechanisms, particularly in cardiomyopathies and other muscular disorders.
The key mechanism of action lies in the loss-of-function approach that these cell lines offer. By eliminating POPDC3 expression, researchers can assess resultant phenotypic changes and alterations in gene expression profiles, providing insights into cellular responses and signaling cascades initiated by POPDC proteins. These insights can lead to breakthroughs in understanding how dysregulation of POPDC proteins contributes to human disease.
In terms of scientific importance, POPDC3 Gene Knockout Cell Lines can be pivotal in both academic and clinical research settings, including drug discovery, regenerative medicine, and the investigation of genetic disorders. They offer a controlled environment for testing therapeutic strategies aimed at restoring normal cellular function or mitigating aberrant cellular behavior resulting from POPDC3 deficiencies.
What sets our POPDC3 Gene Knockout Cell Lines apart from conventional models is their high specificity and reproducibility, which are essential for generating reliable data. Unlike primary cell cultures that may exhibit variability, our knockout lines provide consistent performance across experiments, thus enhancing the reliability of research findings. Moreover, they come with detailed characterization data, which aids researchers in quickly understanding their functional dynamics.
For researchers and clinicians focused on advancing knowledge in molecular biology and related therapeutic applications, POPDC3 Gene Knockout Cell Lines represent a cutting-edge resource. They not only facilitate a deeper understanding of human diseases but also pave the way for the development of novel therapeutic interventions.
As a provider with extensive expertise in biological products, we ensure the highest quality and reliability in our cell line offerings, committed to supporting cutting-edge research with robust and scientifically validated tools.
Please note that all services are for research use only. Not intended for any clinical use.
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