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PHF3 Knockout Cell Lines

Gene: PHF3

Official Full Name: PHD finger protein 3provided by HGNC

Gene Summary: This gene encodes a member of a PHD finger-containing gene family. This gene may function as a transcription factor and may be involved in glioblastomas development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO29252 PHF3 Knockout cell line (HeLa) Human PHF3 1:3~1:6 Negative Online Inquiry
KO29253 PHF3 Knockout cell line (HCT 116) Human PHF3 1:2~1:4 Negative Online Inquiry
KO29254 PHF3 Knockout cell line (HEK293) Human PHF3 1:3~1:6 Negative Online Inquiry
KO29255 PHF3 Knockout cell line (A549) Human PHF3 1:3~1:4 Negative Online Inquiry

Background

PHF3 Gene Knockout Cell Lines are genetically engineered cell lines in which the PHF3 gene has been systematically disrupted or mutated, allowing researchers to study the gene's function and its role in various biological processes. These knockout cell lines provide a powerful tool for examining the contributions of PHF3 to cell growth, differentiation, and response to stimuli, essential for unraveling molecular mechanisms underlying disease states.

The key functionality of PHF3 Gene Knockout Cell Lines lies in their ability to facilitate targeted investigations into the specific roles of the PHF3 gene. By completely ablating PHF3 expression, researchers can observe phenotypic changes in cell behavior and gene expression profiles compared to wild-type counterparts. This process is critical for elucidating the gene's involvement in pathologies, including cancer and developmental disorders, as well as potential therapeutic applications.

The scientific importance of these cell lines extends not only to fundamental research but also to translational medicine, where understanding gene function is essential for developing targeted therapies. In clinical settings, PHF3 knockouts can serve as models for predicting the efficacy of novel drugs aimed at diseases associated with PHF3 dysregulation.

Compared to traditional gene manipulation methods, such as RNA interference, PHF3 Gene Knockout Cell Lines offer the advantage of a stable, heritable alteration that consistently eliminates PHF3 activity without the off-target effects often associated with transient knockdowns. This reliability ensures that findings are reproducible and biologically relevant, making it a superior choice for rigorous scientific inquiry.

For researchers and clinicians, the value of PHF3 Gene Knockout Cell Lines lies in their ability to drive discovery and innovation in understanding gene function and its implications in health and disease. Our company specializes in providing high-quality, validated cell line models that accelerate research and advance scientific knowledge, emphasizing our commitment to excellence in biological product offerings.

Please note that all services are for research use only. Not intended for any clinical use.

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