Gene: PCGF6
Official Full Name: polycomb group ring finger 6provided by HGNC
Gene Summary: The protein encoded by this gene contains a RING finger motif, which is most closely related to those of polycomb group (PcG) proteins RNF110/MEL-18 and BMI1. PcG proteins are known to form protein complexes and function as transcription repressors. This protein has been shown to interact with some PcG proteins and act as a transcription repressor. The activity of this protein is found to be regulated by cell cycle dependent phosphorylation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO06269 | PCGF6 Knockout cell line (HeLa) | Human | PCGF6 | 1:3~1:6 | Negative | Online Inquiry |
KO06270 | PCGF6 Knockout cell line (HCT 116) | Human | PCGF6 | 1:2~1:4 | Negative | Online Inquiry |
KO06271 | PCGF6 Knockout cell line (HEK293) | Human | PCGF6 | 1:3~1:6 | Negative | Online Inquiry |
KO06272 | PCGF6 Knockout cell line (A549) | Human | PCGF6 | 1:3~1:4 | Negative | Online Inquiry |
PCGF6 Gene Knockout Cell Lines are specialized cell lines in which the PCGF6 gene has been deliberately disrupted using advanced genetic engineering techniques, such as CRISPR-Cas9. This product serves as a powerful tool for researchers aiming to investigate the function of the PCGF6 gene and its role in various biological processes, including cell differentiation and oncogenesis.
The key function of PCGF6 Gene Knockout Cell Lines lies in their ability to facilitate the study of gene function through loss-of-function experiments. By providing a model system in which the PCGF6 gene is inactivated, these cell lines allow for the exploration of downstream molecular pathways and phenotypic outcomes. Furthermore, the knockout of this gene can impact significant cellular functions, such as proliferation, apoptosis, and responses to environmental stressors, providing insights into the gene's broader biological significance.
The scientific importance of these cell lines is underscored by their applications in both research and clinical settings. In fundamental research, they are invaluable for dissecting gene regulatory networks and understanding disease mechanisms, especially in cancer biology. Moreover, these cell lines have potential implications in therapeutic development, as targeting PCGF6 may represent a novel strategy for oncological interventions.
Compared to alternative gene manipulation techniques, PCGF6 Gene Knockout Cell Lines offer precision and specificity, minimizing off-target effects commonly associated with traditional gene-editing methods. This high degree of accuracy ensures that scientists can obtain reliable data that is crucial for elucidating the nuanced roles of PCGF6 in cellular contexts.
For researchers and clinicians alike, the value of PCGF6 Gene Knockout Cell Lines cannot be overstated. They provide a robust platform for experimental reproducibility and promise enhanced insights into genes that hold potential as therapeutic targets.
Our company specializes in the development of cutting-edge biological tools, backed by years of expertise in gene editing and cellular biology. We are committed to empowering researchers with innovative solutions that drive scientific discovery and improve clinical outcomes.
Please note that all services are for research use only. Not intended for any clinical use.
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