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PACSIN3 Knockout Cell Lines

Gene: PACSIN3

Official Full Name: protein kinase C and casein kinase substrate in neurons 3provided by HGNC

Gene Summary: This gene is a member of the protein kinase C and casein kinase substrate in neurons family. The encoded protein is involved in linking the actin cytoskeleton with vesicle formation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO03103 PACSIN3 Knockout cell line (HeLa) Human PACSIN3 1:3~1:6 Negative Online Inquiry
KO03104 PACSIN3 Knockout cell line (HCT 116) Human PACSIN3 1:2~1:4 Negative Online Inquiry
KO03105 PACSIN3 Knockout cell line (HEK293) Human PACSIN3 1:3~1:6 Negative Online Inquiry
KO03106 PACSIN3 Knockout cell line (A549) Human PACSIN3 1:3~1:4 Negative Online Inquiry

Background

PACSIN3 Gene Knockout Cell Lines are engineered cellular models designed to specifically disrupt the PACSIN3 gene, which plays a critical role in endocytosis and membrane trafficking within various cell types. By utilizing the CRISPR-Cas9 gene editing technology, these knockout cell lines provide precise modifications that allow researchers to study the functional consequences of PACSIN3 deficiency. The mechanism of action involves the introduction of targeted double-strand breaks in the DNA, leading to disruptions in the gene's coding sequence. This results in loss-of-function mutations, enabling a detailed analysis of PACSIN3's contributions to cellular pathways and physiological processes.

The importance of PACSIN3 in both fundamental research and clinical applications cannot be overstated, as studies suggest its involvement in neurodegenerative diseases, cancer progression, and cellular stress responses. These knockout cell lines serve as invaluable tools for researchers developing therapies that target cellular mechanisms associated with these conditions. By employing PACSIN3 gene knockout cell lines, scientists can elucidate the pathways influenced by PACSIN3, thus identifying potential therapeutic targets or biomarkers.

What sets our PACSIN3 Gene Knockout Cell Lines apart from conventional gene-modified models is their unparalleled specificity and reliability. These cell lines undergo rigorous validation processes to ensure consistent performance and reproducibility, making them ideal for high-throughput screenings and detailed mechanistic studies. Additionally, they are compatible with a wide range of assays, including drug response tests and protein interaction studies.

Researchers and clinicians will find that the use of PACSIN3 Gene Knockout Cell Lines enhances the rigor and depth of their investigations, ultimately accelerating the journey from basic research to clinical translation. Our company is committed to advancing scientific inquiry by providing high-quality biological products and expertise, ensuring that our customers have the resources they need for successful outcomes in their research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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